Experimental combo aims to outsmart tough leukemia
NCT ID NCT05627232
First seen Nov 03, 2025 · Last updated Apr 24, 2026 · Updated 23 times
Summary
This early-phase study is testing two different drug combinations for people whose acute myeloid leukemia (AML) has come back or not responded to prior treatment. In one part, patients receive tazemetostat plus standard chemotherapy (CPX-351); in the other, they get palbociclib before chemotherapy. The main goal is to check safety and find the best dose, with about 24 adults taking part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Thomas Jefferson University Hospital
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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