Medical University Of Graz

This study looks at whether giving a special mix of medicines (fibrinogen, plasma, and tranexamic acid) to trauma patients with life-threatening bleeding before they get to the hospital is possible and helpful. Ten adults with severe bleeding from injury will receive this treatme…

This study tests whether transplanting healthy donor stool into the gut can help people with severe gut complications after a stem cell transplant. About 15 participants with steroid-resistant graft-versus-host disease will receive the treatment via colonoscopy. The goal is to re…

This study compares two methods to rebuild jawbone for people missing teeth. One uses bone from the patient's own body, the other uses donated bone. Researchers want to see if both work equally well and are safe. About 26 adults with too little jawbone for dental implants will ta…

This study tests whether a large dose of vitamin D3 can lower the risk of death within 28 days for critically ill adults who are severely deficient in vitamin D. Researchers aim to enroll 2,400 patients in intensive care units. Earlier research suggested a strong survival benefit…

This study tests a new way to manage bleeding risk in people with liver cirrhosis who need a TIPS procedure (a shunt placed in the liver). Instead of standard care, doctors will use a special blood test (thrombelastography) to decide if and when to give blood products before the …

This study tests a new, non-invasive tool called the POPScore to predict infections in newborns with breathing problems. The score combines light measurements of muscle oxygen with routine vital signs like heart rate. Researchers will check if the score, taken within 6 hours of b…

This study tests a portable DNA analyzer (Nanopore MinION) to quickly identify bacteria or fungi causing endophthalmitis, a severe eye infection. Researchers will compare the new method with standard lab cultures using samples from 20 patients. If successful, this approach could …

This study looks at how alcohol affects tremors in people with essential tremor, dystonia, and Parkinson's disease. 45 participants will receive either an alcoholic drink or a non-alcoholic placebo on two separate days. Researchers will measure tremor changes using a device and c…

This study is observing 250 pregnant women diagnosed with preeclampsia to better understand how this serious condition develops and affects both mother and baby. Researchers will collect health data and samples during pregnancy, at birth, and after delivery. The goal is to learn …

This study looks at whether a detailed, easy-to-understand explanation of a functional neurological movement disorder helps patients better grasp their condition and feel more satisfied with their care. About 35 adults with conditions like functional paralysis or tremors will rec…

This study follows 800 pregnant women—some healthy, some with obesity or diabetes—to understand how these conditions affect both mother and baby's health over time. Researchers will track body composition, blood sugar, blood pressure, and other markers during pregnancy and after …

This study is a registry that collects information from 1,500 people with advanced pancreatic cancer in Austria. Researchers will track which treatments patients receive and how they respond, including side effects. The goal is to learn from real-world experiences to help guide f…

This study tests a new, non-invasive device that uses light to measure oxygen levels in the brain's small blood vessels of newborns immediately after birth. Researchers will monitor 40 term and preterm babies to see if this method can provide more detailed information than curren…

This study looks back at medical records of 1000 adults with COPD who had a special heart test. The goal is to learn more about a condition called pulmonary hypertension, where blood vessels in the lungs are under high pressure. By analyzing past data, researchers hope to better …

This study is a registry that will collect information from about 1000 people with hypertrophic cardiomyopathy (a condition where the heart muscle is thickened) across multiple clinics in Austria. Researchers will gather data from medical records, tests, and genetic testing to be…

This study looks at how Boswellia serrata, a natural herb used in Ayurvedic medicine, changes the way healthy adults feel and process pain. Researchers will use a capsaicin (chili pepper) cream to create temporary pain and then measure pain intensity and nerve responses. The goal…

This study aims to find out how common functional neurological disorders are in people who already have a movement disorder like Parkinson's disease, tremor, or dystonia. Researchers will examine 216 adults aged 18 to 80 using neurological exams, thinking tests, and questionnaire…

This study tracks 100 adults who had a heart attack to see how many develop anxiety or posttraumatic stress disorder (PTSD) later on. Researchers want to understand if early feelings of fear, stress, and pain during the heart attack raise the risk of long-term mental health probl…

This study watches how deeply heart surgery patients are sedated in the ICU using a brain activity monitor (BIS). The care team won't see the readings, so they treat patients as usual. Researchers will track 50 patients for 48 hours to see how often deep sedation happens and if i…

This study looks at whether a blood test called BAT inhibition can tell if venom immunotherapy (allergy shots) has protected people from future insect stings. Currently, the only reliable way to check is by stinging patients with live insects, which is not widely available. Resea…

This study aims to find a simple blood test to detect pulmonary hypertension early in people with chronic lung diseases like COPD or pulmonary fibrosis. Researchers will analyze collagen fragments in blood and lung tissue from 80 participants to create a molecular fingerprint of …

This study looks at why bee venom immunotherapy (allergy shots) is less effective for some people. Researchers will test 266 adults with bee sting allergies to see if having a strong allergy to a specific bee venom protein (Api m 10) makes treatment more likely to fail. The goal …

This study is creating a large database of information from 900 people who have pulmonary hypertension (high blood pressure in the lungs) or are at risk for it. Researchers will collect medical history, test results, and follow-up data over time. The goal is to better understand …

This study follows 400 pregnant women diagnosed with gestational diabetes to learn how the condition affects both mother and baby during pregnancy and after birth. Researchers will collect health data and samples from mothers and infants at several points, including after deliver…

This study is creating a database to help doctors find interstitial lung disease (ILD) earlier in people who have other systemic diseases that put them at risk. Researchers will track lung function tests like DLCO and FVC in 412 adults to see if a screening program can catch ILD …

This study tests whether doing hand movements in virtual reality can reduce tremors in people with functional movement disorder. Researchers will measure reaction time, tremor duration, and brain activity using EEG. The study includes 48 adults with functional tremor, essential t…

This study looks at how the bacteria in your gut (the microbiome) might be linked to diarrhea caused by cancer treatments. Researchers will follow 150 adults starting cancer therapy and collect stool and blood samples to see if certain gut bacteria or markers in the body predict …