New DNA scanner could speed up diagnosis of eye infections

NCT ID NCT05372861

Recruiting now Diagnosis Sponsor: Medical University of Graz Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing whether a portable DNA sequencing device (Oxford Nanopore MinION) can quickly and accurately identify the bacteria or fungi causing endophthalmitis, a severe eye infection. Researchers will compare the new method's results and speed against standard lab cultures. The study involves 20 patients with endophthalmitis who are having vitrectomy surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nanopore sequencing (Oxford Nanopore MinION device)
What this could lead to: If successful, this method could provide faster and more accurate identification of the germs causing serious eye infections, helping doctors choose the right treatment sooner.
What could go wrong: This is a very small pilot study with only 20 participants, so results may not apply to all patients. The new sequencing method may not prove more reliable than standard lab cultures.

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Conditions

The condition(s) this trial relates to.

endophthalmitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOPHTHALMITIS

Contacts and locations

Locations

Universitäts Augenklinik Graz
RECRUITING

Graz, Styria, 8036, Austria

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