Medical University Of Graz

This study compares two methods of rebuilding jawbone in people who have lost bone and need dental implants. One method uses the patient's own bone, and the other uses donated (allogeneic) bone. The goal is to see if both approaches are equally safe and effective at restoring eno…

This study tests whether putting healthy donor stool into the gut can help people with severe gut inflammation after a stem cell transplant. The condition, called gastrointestinal graft-versus-host disease, is hard to treat and often deadly. Fifteen patients will receive the stoo…

This study is testing whether giving high doses of vitamin D3 to critically ill patients with very low vitamin D levels can reduce the chance of death within 28 days. The trial will include 2,400 adults in intensive care units. If successful, this cheap and easy treatment could b…

This study tests a new, non-invasive tool called the POP-Score to predict infection in newborns within the first 6 hours of life. The score combines light-based measurements of muscle oxygen with routine vital signs like heart rate and blood pressure. Researchers will enroll 93 n…

This study looks for early signs of pulmonary hypertension (high blood pressure in the lungs) in people with chronic lung diseases like COPD or pulmonary fibrosis. Researchers will analyze collagen fragments in blood and lung tissue to create a 'fingerprint' that could lead to si…

This pilot study is testing whether a portable DNA sequencing device (Oxford Nanopore MinION) can quickly and accurately identify the bacteria or fungi causing endophthalmitis, a severe eye infection. Researchers will compare the new method's results and speed against standard la…

This study tests whether a blood test called BAT inhibition can replace live insect sting challenges for people with wasp venom allergy. Currently, sting challenges are the only reliable way to see if venom immunotherapy is working, but they are not widely available. Researchers …

This study looks at whether giving surfactant (a lung treatment) over 1 minute or 5 minutes helps very premature babies (under 28 weeks) stay more stable. The goal is to see which speed leads to better oxygen levels in the blood and brain. 76 babies will take part, and the result…

This study tests a new device called the Spur scaffold, used with a drug-coated balloon, to treat blocked arteries below the knee in people with chronic limb-threatening ischemia (CLTI). The study includes 40 high-risk patients—those with diabetes or on dialysis—and measures how …

This study looks at how blood transfusions affect tiny molecules called peroxides in very premature babies. These molecules can damage cells if they build up. Researchers will measure peroxide levels before and after transfusions, and also use a special light device to check oxyg…

This study is testing whether a 12-week home-based walking program can change the immune system in people with lung cancer. Fifty patients will either do moderate continuous walking, high-intensity interval walking, or receive standard exercise advice. Researchers will measure ch…

This study looks at whether the bacteria naturally found in urine can help doctors better understand melanoma, a serious skin cancer, and predict how well patients will respond to treatment. Researchers will collect urine and stool samples from 50 people with advanced melanoma st…

This study tests whether a structured, empathetic explanation of a functional neurological movement disorder diagnosis helps patients understand their illness better and feel more satisfied. About 35 adults with conditions like functional tremor or seizures will receive the speci…

This study follows 800 pregnant women—some healthy, some with obesity or diabetes—to understand how these conditions affect both mother and baby during pregnancy and after birth. Researchers will track body composition, blood sugar, blood pressure, and other health markers throug…

This study follows 400 pregnant women diagnosed with gestational diabetes to understand how it affects their health and their baby's health. Researchers will track things like blood sugar, blood pressure, and body fat during pregnancy and after birth. The goal is to learn more ab…

This study is following 250 pregnant women diagnosed with preeclampsia, a serious condition involving high blood pressure and organ problems. Researchers will collect health data and samples from mothers and babies during pregnancy, at birth, and a few months after. The goal is t…

This study looks back at medical records of 1,000 people with COPD who also had a special heart test called right heart catheterization. Researchers want to understand a specific lung-heart problem called pulmonary hypertension. By analyzing this data, they hope to better identif…

This study is creating a large database of information from 900 people who have pulmonary hypertension (high blood pressure in the lungs) or are at risk for it. Researchers will collect medical history, test results, and follow-up data over time. The goal is to improve understand…

This study is creating a database to help doctors find early signs of interstitial lung disease (ILD) in people who have other health conditions that put them at risk. About 412 adults with such conditions will be screened and followed over time. The goal is to improve early dete…

This study looks at whether a special combination of blood products and medication (fibrinogen, plasma, and tranexamic acid) can be given to trauma patients with life-threatening bleeding while still in the ambulance. The goal is to see if this approach is practical and safe. Onl…

This study looks at whether a special blood test called thrombelastography can help doctors decide when to give blood products to people with liver cirrhosis who are getting a TIPS shunt. The goal is to see if this test reduces the amount of blood products used and prevents bleed…

This study is investigating why bee venom immunotherapy (VIT) doesn't work for some people. Researchers will test blood samples from 266 adults with bee venom allergy before they start treatment. They want to see if having a strong allergic response to a specific bee venom compon…

This study is a registry that will collect health information from 1000 people with hypertrophic cardiomyopathy (HCM) across Austria. Researchers will track symptoms, medical history, test results, and genetics to better understand the disease and improve future care. Participant…

This study looks at how the bacteria in your gut might influence diarrhea caused by cancer treatments. Researchers will follow 150 adults starting cancer therapy, collecting stool and blood samples to analyze gut microbiome changes. The goal is to better understand why some peopl…

This registry is collecting information from 1,500 people with advanced pancreatic cancer in Austria to see how different chemotherapy treatments work in everyday practice. Researchers will track which treatments are used, how well they work, and what side effects occur. The goal…

This study tests a new, non-invasive light-based device that measures oxygen levels in the brain's small blood vessels of newborns immediately after birth. Researchers want to see if this method can give doctors a clearer picture of brain health during the critical transition fro…

This pilot study is testing whether virtual reality motor tasks can help understand functional tremor, a type of movement disorder. Researchers will measure reaction time and brain activity in 48 people with functional tremor, essential tremor, or healthy controls. The goal is to…

This observational study at the Medical University of Graz will examine 216 people with movement disorders like Parkinson's, tremor, or dystonia to see how many also have functional neurological symptoms. Participants will undergo neurological exams, cognitive tests, and question…

This study tracks 100 heart attack survivors to see how many develop anxiety or posttraumatic stress disorder (PTSD) in the long run. Researchers will measure early pain, stress, and anxiety levels to understand their impact on mental health. The goal is to identify those at risk…

This study is testing whether a supplement called Boswellia serrata (also known as frankincense) can change how healthy people feel pain. Twelve volunteers will take either the supplement or a placebo for a short time, then have a small amount of capsaicin (the stuff that makes c…