Medical University Of Graz

This study tests whether putting healthy donor stool into the gut can help people with severe gut inflammation after a stem cell transplant. The condition, called gastrointestinal graft-versus-host disease, is hard to treat and often deadly. Fifteen patients will receive the stoo…

People with atrial fibrillation face a higher risk of stroke, and doctors often prescribe blood thinners to lower it. Some cannot take those drugs safely. This registry collects information on everyone in Austria who receives left atrial appendage closure, a device procedure that…

This study compares two methods of rebuilding jawbone in people who have lost bone and need dental implants. One method uses the patient's own bone, and the other uses donated (allogeneic) bone. The goal is to see if both approaches are equally safe and effective at restoring eno…

Researchers at University Hospital Graz are studying how closely upper-arm cuff blood pressure readings match readings from a small tube placed in an artery during the first minutes of general anesthesia. The study includes 120 high-risk patients who already need an arterial cath…

This pilot study is testing whether a portable DNA sequencing device (Oxford Nanopore MinION) can quickly and accurately identify the bacteria or fungi causing endophthalmitis, a severe eye infection. Researchers will compare the new method's results and speed against standard la…

Researchers want to find out if they can predict which patients with a pacemaker or implanted defibrillator will develop atrial fibrillation, a heart rhythm problem that raises stroke risk. They will enroll 250 people with these devices and a higher stroke risk score. Participant…

This study tests whether a blood test called BAT inhibition can replace live insect sting challenges for people with wasp venom allergy. Currently, sting challenges are the only reliable way to see if venom immunotherapy is working, but they are not widely available. Researchers …

This pilot study is testing whether a rapid, point-of-care blood test can help identify early signs of infection and sepsis in preterm infants. Researchers will measure inflammatory markers like IL-6, PCT, CRP, and MxA in blood samples from about 40 to 80 premature babies, compar…

This study tests a new, non-invasive tool called the POP-Score to predict infection in newborns within the first 6 hours of life. The score combines light-based measurements of muscle oxygen with routine vital signs like heart rate and blood pressure. Researchers will enroll 93 n…

This study looks for early signs of pulmonary hypertension (high blood pressure in the lungs) in people with chronic lung diseases like COPD or pulmonary fibrosis. Researchers will analyze collagen fragments in blood and lung tissue to create a 'fingerprint' that could lead to si…

This study examines whether placing preterm infants (born between 26 and 32 weeks) skin-to-skin with a parent immediately after birth is safe and feasible. Typically, preterm babies receive skin-to-skin care within 24 hours. Researchers will compare immediate skin-to-skin care to…

This study looks at whether giving surfactant (a lung treatment) over 1 minute or 5 minutes helps very premature babies (under 28 weeks) stay more stable. The goal is to see which speed leads to better oxygen levels in the blood and brain. 76 babies will take part, and the result…

This study tests a new, non-invasive light-based device that measures oxygen levels in the brain's small blood vessels of newborns immediately after birth. Researchers want to see if this method can give doctors a clearer picture of brain health during the critical transition fro…

This study tests a new device called the Spur scaffold, used with a drug-coated balloon, to treat blocked arteries below the knee in people with chronic limb-threatening ischemia (CLTI). The study includes 40 high-risk patients—those with diabetes or on dialysis—and measures how …

This study looks at whether a special blood test called thrombelastography can help doctors decide when to give blood products to people with liver cirrhosis who are getting a TIPS shunt. The goal is to see if this test reduces the amount of blood products used and prevents bleed…

Many people with liver cirrhosis lose muscle, a condition called sarcopenia that raises the risk of complications and death. Researchers suspect that changes in gut bacteria play a role because the microbiome helps the body absorb and use nutrients. This study follows 120 hospita…

Researchers at the Medical University of Graz are setting up a biobanking study to study sarcopenia, or muscle loss, in people with liver cirrhosis and chronic inflammatory bowel disease. They plan to enroll 1,000 adults who have a routine CT or MRI scan, collecting clinical data…

This study is investigating why bee venom immunotherapy (VIT) doesn't work for some people. Researchers will test blood samples from 266 adults with bee venom allergy before they start treatment. They want to see if having a strong allergic response to a specific bee venom compon…

People on hemodialysis often drop blood pressure during treatment, which can strain the heart and brain. Researchers compare standard hemodialysis with isolated ultrafiltration, a method that removes fluid without the usual solute-clearing step. The study measures changes in bloo…

This study looks at whether getting an mRNA COVID-19 vaccine within three months before starting immunotherapy improves outcomes for people with liver cancer. Researchers will review medical records of 200 patients in Austria to compare response rates, survival, and side effects …

This study looks at whether two blood-clotting products — human fibrinogen and freeze-dried plasma — remain stable when stored in an ambulance under everyday conditions, including summer heat. Researchers in Graz, Austria, will compare samples stored in the ambulance with ones ke…

This study looks at whether a blood test (liquid biopsy) can help diagnose and monitor cartilage tumors called chondrosarcomas. Researchers will collect blood samples from 60 patients before and after surgery, and during follow-up for two years. They will look for specific geneti…

This pilot study is testing whether a wireless adhesive thermometer can safely and accurately monitor body temperature in newborns undergoing therapeutic hypothermia, a cooling treatment for brain injury. Currently, temperature is tracked with an invasive rectal probe, which carr…

This study tests whether a small, wireless adhesive thermometer can continuously monitor the body temperature of preterm babies (born between 32 and 37 weeks) during the first 15 minutes after birth, as well as their mothers during delivery. The goal is to see if this non-invasiv…

This registry is collecting information from 1,500 people with advanced pancreatic cancer in Austria to see how different chemotherapy treatments work in everyday practice. Researchers will track which treatments are used, how well they work, and what side effects occur. The goal…

This study looks at how blood transfusions affect tiny molecules called peroxides in very premature babies. These molecules can damage cells if they build up. Researchers will measure peroxide levels before and after transfusions, and also use a special light device to check oxyg…

This study is testing whether a 12-week home-based walking program can change the immune system in people with lung cancer. Fifty patients will either do moderate continuous walking, high-intensity interval walking, or receive standard exercise advice. Researchers will measure ch…

This study looks at whether the bacteria naturally found in urine can help doctors better understand melanoma, a serious skin cancer, and predict how well patients will respond to treatment. Researchers will collect urine and stool samples from 50 people with advanced melanoma st…

This study tests whether a structured, empathetic explanation of a functional neurological movement disorder diagnosis helps patients understand their illness better and feel more satisfied. About 35 adults with conditions like functional tremor or seizures will receive the speci…

This study follows 800 pregnant women—some healthy, some with obesity or diabetes—to understand how these conditions affect both mother and baby during pregnancy and after birth. Researchers will track body composition, blood sugar, blood pressure, and other health markers throug…

This study follows 400 pregnant women diagnosed with gestational diabetes to understand how it affects their health and their baby's health. Researchers will track things like blood sugar, blood pressure, and body fat during pregnancy and after birth. The goal is to learn more ab…

This study is following 250 pregnant women diagnosed with preeclampsia, a serious condition involving high blood pressure and organ problems. Researchers will collect health data and samples from mothers and babies during pregnancy, at birth, and a few months after. The goal is t…

This study looks back at medical records of 1,000 people with COPD who also had a special heart test called right heart catheterization. Researchers want to understand a specific lung-heart problem called pulmonary hypertension. By analyzing this data, they hope to better identif…

This study is creating a large database of information from 900 people who have pulmonary hypertension (high blood pressure in the lungs) or are at risk for it. Researchers will collect medical history, test results, and follow-up data over time. The goal is to improve understand…

This study is creating a database to help doctors find early signs of interstitial lung disease (ILD) in people who have other health conditions that put them at risk. About 412 adults with such conditions will be screened and followed over time. The goal is to improve early dete…

This study looks at whether a special combination of blood products and medication (fibrinogen, plasma, and tranexamic acid) can be given to trauma patients with life-threatening bleeding while still in the ambulance. The goal is to see if this approach is practical and safe. Onl…

This study is a registry that will collect health information from 1000 people with hypertrophic cardiomyopathy (HCM) across Austria. Researchers will track symptoms, medical history, test results, and genetics to better understand the disease and improve future care. Participant…

This study looks at how the bacteria in your gut might influence diarrhea caused by cancer treatments. Researchers will follow 150 adults starting cancer therapy, collecting stool and blood samples to analyze gut microbiome changes. The goal is to better understand why some peopl…

This pilot study is testing whether virtual reality motor tasks can help understand functional tremor, a type of movement disorder. Researchers will measure reaction time and brain activity in 48 people with functional tremor, essential tremor, or healthy controls. The goal is to…

This observational study at the Medical University of Graz will examine 216 people with movement disorders like Parkinson's, tremor, or dystonia to see how many also have functional neurological symptoms. Participants will undergo neurological exams, cognitive tests, and question…

This study tracks 100 heart attack survivors to see how many develop anxiety or posttraumatic stress disorder (PTSD) in the long run. Researchers will measure early pain, stress, and anxiety levels to understand their impact on mental health. The goal is to identify those at risk…

This study is testing whether a supplement called Boswellia serrata (also known as frankincense) can change how healthy people feel pain. Twelve volunteers will take either the supplement or a placebo for a short time, then have a small amount of capsaicin (the stuff that makes c…