New study aims to unlock secrets of bee venom therapy failures

NCT ID NCT04259359

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is investigating why bee venom immunotherapy (VIT) doesn't work for some people. Researchers will test blood samples from 266 adults with bee venom allergy before they start treatment. They want to see if having a strong allergic response to a specific bee venom component, called Api m 10, predicts treatment failure. The goal is to improve future allergy shots so more people are protected from severe reactions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bee venom immunotherapy

What this could lead to

If successful, this could help doctors identify which patients are at risk of treatment failure and lead to better, more personalized bee venom allergy treatments.

What could go wrong

This is an observational study, not a treatment trial. It may not directly change care, and results might not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

venom allergy Venom Hypersensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Dermatology and Venerology, Medical University of Graz

    RECRUITING

    Graz, 8036, Austria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Elbe Klinikum Buxtehude

    RECRUITING

    Buxtehude, 21614, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario de Castellón

    RECRUITING

    Castellon, 12004, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••