New scaffold device tested to save legs in High-Risk patients

NCT ID NCT07465627

First seen Jun 25, 2026 · Last updated Jul 02, 2026 · Updated 3 times

Summary

This study tests a new device called the Spur scaffold, used with a drug-coated balloon, to treat blocked arteries below the knee in people with chronic limb-threatening ischemia (CLTI). The study includes 40 high-risk patients—those with diabetes or on dialysis—and measures how much the artery recoils (shrinks back) within 15 minutes after treatment. The goal is to see if this approach works better for these difficult-to-treat patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Spur Peripheral Retrievable Scaffold System with a drug-coated balloon
What this could lead to
If successful, this could help doctors understand how to better treat blocked leg arteries in high-risk patients, potentially reducing amputations.
What could go wrong
This is a very small, early study (40 people) that only measures immediate vessel recoil, not long-term outcomes. It may not lead to better treatments or apply to all patients.

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Conditions

The condition(s) this trial relates to.

Chronic Limb-Threatening Ischemia limb ischemia peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical University of Graz, Division of Angiology

    RECRUITING

    Graz, Austria

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