Poop pills? no, a colonoscopy with donor stool to fight a deadly transplant complication

NCT ID NCT03819803

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether putting healthy donor stool into the gut can help people with severe gut inflammation after a stem cell transplant. The condition, called gastrointestinal graft-versus-host disease, is hard to treat and often deadly. Fifteen patients will receive the stool via colonoscopy to see if it calms the inflammation and improves survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fecal microbiota from a healthy donor

What this could lead to

If it works, this could offer a new way to control severe gut inflammation after stem cell transplants, reducing the need for strong immune-suppressing drugs.

What could go wrong

This is a very small early-phase trial with only 15 people. The treatment involves colonoscopy and carries risks like infection or complications. It may not work for everyone or lead to lasting benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute graft versus host disease graft versus host disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz

    RECRUITING

    Graz, Styria, 8036, Austria

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact