Massive trial tests antibiotic jab to stop blinding infection after cataract surgery
NCT ID NCT03244072
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will test whether a single antibiotic injection given during cataract surgery can prevent endophthalmitis, a rare but severe eye infection. About 60,000 people with cataracts will receive either the antibiotic or a placebo. The goal is to see if the antibiotic reduces the number of infections after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
moxifloxacin (antibiotic eye injection)
What this could lead to
If it works, this could become a standard way to prevent a rare but serious eye infection after cataract surgery.
What could go wrong
This is a large but still early-phase trial. The infection is already rare, so proving a benefit is challenging, and there is a small risk of allergic reaction or injection-related side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Zion Eye Institute
St. George, Utah, 84790, United States
Contact