Fondation Ophtalmologique Adolphe De Rothschild

This study tested a newer method called ADAPT that uses suction to remove blood clots from the brain during a stroke. It involved 381 adults with large-vessel blockages treated within 6 hours of symptoms. The goal was to see if ADAPT could restore blood flow more completely than …

This study tested whether a drug called dornase alfa (Pulmozyme) can help open small blood vessels in the brain after a stroke. The trial included 39 people who had a stroke caused by a clot and were already receiving standard clot-busting medicine and a procedure to remove the c…

This study looked at whether using a much lower dose of gadolinium (a contrast dye) in MRI scans can still spot meningiomas (common brain tumors) as well as the standard full dose. Over 500 adults having a brain MRI for screening or follow-up of meningioma took part. The goal is …

This study looked at whether advanced high-resolution MRI can help doctors more accurately diagnose the cause of optic disc swelling (a sign of various eye or brain conditions). Researchers tested the new MRI technique on 197 adults with optic disc edema to see if it improved dia…

This study tested a budesonide nasal spray in 120 adults who lost their sense of smell after COVID-19 and still had the problem 30 days later. The goal was to see if the spray could improve smell scores after 30 days of treatment. The approach is based on the idea that persistent…

This study tested a technique called thermocoagulation in 100 children with drug-resistant focal epilepsy. During a brain monitoring procedure, doctors applied heat to the seizure-starting area to create tiny lesions, aiming to reduce seizure frequency. The goal was to see if thi…

This small study tested whether spinal cord stimulation can improve walking in people with Parkinson's disease whose symptoms are not well controlled by medication. Five participants received a spinal cord stimulator, and researchers measured changes in walking ability and freezi…

This study looked at whether special eye imaging (adaptive optics) can detect changes in the tiny blood vessels at the back of the eye in people who recently had a stroke. Researchers compared 91 participants — those with ischemic or hemorrhagic stroke and healthy controls — to m…

This study looked at two different scanning methods to monitor wet age-related macular degeneration (AMD) in 68 adults aged 50 and older who were already receiving anti-VEGF injections as needed. The goal was to see if using a newer type of scan (OCT angiography) instead of the s…

This study tested French versions of two questionnaires that measure how much hearing aids help people. Researchers wanted to make sure the translations are accurate and reliable. 100 adults with hearing loss who use hearing aids took part. The goal is to give doctors better tool…

This study looked at whether cooling the body based on brain temperature, rather than standard body temperature, is more effective for severe brain injury patients with fever. 41 adults were enrolled and divided into two groups: one where cooling was guided by brain temperature a…

This study used a special eye scanner (SD-OCT) to look at tiny granules in the retina of 20 healthy adults. The goal was to describe these granules and see how they change with time and light. This is basic research to help future studies on eye diseases that affect the retina.

This study looked at 71 adults suspected of having a rare, non-cancerous brain tumor called MVNT. Researchers used special MRI scans to find unique patterns that could help doctors tell MVNT apart from other similar-looking brain conditions. The goal was to improve diagnosis, not…

This study looked at whether using ultrasound to guide a needle into the femoral artery (in the groin) helps doctors succeed on the first try in children. 149 children who needed this procedure for brain imaging or treatment took part. The goal was to see if ultrasound reduces th…

This study looked at eye damage in 34 people who were hospitalized for severe COVID-19. Researchers used special eye imaging to find problems like inflammation, blood clots, and nerve damage that could threaten vision. The goal was to better understand how COVID-19 affects the ey…

This study looked at whether a special type of MRI scan, called IVIM, can help predict how well people recover three months after a stroke. Researchers scanned 274 adults who had a stroke and compared the scan results to their recovery scores. The goal was to see if the scan coul…

This study looked at how a contrast dye called gadolinium changes a special MRI measurement called QSM in people with white matter disease. 73 adults had an MRI without dye, then with dye (as part of their regular care), and then another without dye. The goal was to see if the dy…

This study tested a new questionnaire designed to measure how well babies (0-36 months old) with eye diseases can see, even before they can talk. The goal was to see if the questionnaire is accurate and reliable, so doctors can better decide when to perform surgery. 150 children …

This study looked at eye problems in 23 COVID-19 patients in intensive care. Researchers checked for damage to the cornea, retina, and optic nerve to find and treat issues early. The goal was to prevent permanent vision loss in these seriously ill patients.

This study tested two different MRI scan methods to see how well they find a specific sign of multiple sclerosis (MS) called the central vein sign. Researchers compared a standard scan with an optimized version in 60 adults with early-stage MS. The goal was to improve how doctors…

This study tested two different MRI techniques to see which one better detects active brain lesions in people with multiple sclerosis (MS). 180 adults with MS or similar conditions had brain scans after a recent symptom flare-up. The goal was to find the most sensitive method for…

This study involved 13 adults with drug-resistant epilepsy to create a database for developing a seizure detection algorithm. Researchers used a wearable patch to record heart rate and movement, while patients also underwent video-EEG monitoring as the gold standard. The goal is …

This study tested whether an artificial intelligence (AI) algorithm could accurately diagnose multiple neuro-ophthalmologic and neurologic conditions—such as optic nerve diseases and brain tumors—from standard retinal images. Researchers analyzed data from 693 patients with confi…

This study looked at 455 people who had a stroke and were treated with a procedure to remove a blood clot. Researchers compared two ways of measuring blood pressure in the first 24 hours after treatment: a continuous monitor versus a standard arm cuff. The goal was to see which m…

This study checked if leftover COVID-19 virus in the nose is linked to ongoing brain fog and memory problems. Researchers compared 51 adults who had COVID-19 months earlier—some with brain fog, some without. They looked for virus in the nasal cavity and matched it to thinking dif…

This study looked at 63 people who had a sudden loss of vision from a blocked artery in the eye (called CRAO). Researchers used advanced MRI scans to find signs of the blockage and related problems in the brain. The goal was to improve diagnosis and predict how well vision might …

This study tested whether a technique called compressed sensing can make MRI scans faster while still producing clear images. 82 people having routine brain MRIs had extra sequences added to their scan. The goal was to see if the faster scans matched the standard ones in quality.

This study looked at whether a single central monitoring station outside the operating room can safely oversee patients during common eye surgeries like cataract removal, instead of having a dedicated anesthesia nurse in each room. About 900 adults having eye surgery with local a…

This study looked at 20 adults who have a flat fovea (fovea plana) in their retina but no vision issues or known albinism. Researchers used eye scans and genetic tests to see if these people carry gene changes linked to albinism. The goal was to understand why some people have th…