Fondation Ophtalmologique Adolphe De Rothschild

This study compares two ways to remove large blood clots from the brain during a stroke: direct aspiration (ADAPT) and using a stent retriever. About 381 adults with stroke caused by a blocked artery in the front part of the brain took part. The goal is to see which method clears…

This study tested whether a drug called dornase alfa (Pulmozyme) can help restore full blood flow to the brain after a stroke. The trial included 39 people who had a stroke and were already receiving standard clot-busting medication and a mechanical clot removal procedure. The go…

This study tested whether cooling the brain based on its own temperature, rather than body temperature, improves fever control in severe brain injury patients. 41 adults with brain injury and fever were enrolled. The intervention group used an external cooling device guided by br…

This study tested whether special MRI scans can better detect signs of central retinal artery occlusion (CRAO), also known as an eye stroke. Researchers enrolled 63 adults with CRAO and performed detailed brain and eye imaging. The goal was to find imaging clues that help diagnos…

This study looked at whether a new, high-resolution MRI can help doctors more accurately and confidently diagnose the cause of optic disc swelling (a sign of various eye or brain problems). Researchers used these detailed scans on 197 adults with optic disc swelling to see if the…

This study tested two different MRI scanning methods to see which better detects the 'central vein sign' in the brains of people with multiple sclerosis (MS). The central vein sign is a marker that helps doctors diagnose MS more accurately. Sixty adults with early-stage MS underw…

This study tested two different MRI sequences to see which one better detects active inflammatory lesions in the brains of people with multiple sclerosis (MS). 180 adults with known central nervous system inflammatory disease who needed an MRI after a recent clinical event took p…

This study looked at whether using a much lower dose of gadolinium (a contrast dye) in MRI scans can still find meningiomas (a type of brain tumor) as well as the standard full dose. Over 500 adults getting a brain MRI for screening or follow-up took part. The goal is to reduce t…

Researchers tested an artificial intelligence program that analyzes retinal images to diagnose several nerve and brain conditions, such as optic neuropathy and brain tumors. The study used data from 693 patients with confirmed diagnoses. The goal is to create a fast triage tool f…

This study looked at using a heat-based technique called thermocoagulation in 100 children aged 1.5 to 17 years with focal epilepsy that doesn't respond to medication. During a brain monitoring procedure, doctors applied small heat lesions to the area where seizures start, aiming…

This study tested whether a budesonide nasal rinse (a steroid) could improve smell loss in 120 adults who still had trouble smelling 30 days after a mild COVID-19 infection. Participants used the rinse twice daily for 30 days, along with smell training. The goal was to see if mor…

This study tested whether electrical stimulation of the spinal cord could improve walking in people with Parkinson's disease whose symptoms are not well controlled by medication. Five participants received a spinal cord stimulator, and researchers measured changes in walking abil…

This study looked at 455 stroke patients to see if a continuous finger blood pressure monitor (Clearsight) or standard arm cuff measurements better predict brain bleeding after clot removal. Each patient had both methods used within 24 hours after treatment. The goal was to see w…

This study tested whether a special MRI scan called IVIM can predict how well people recover three months after an acute ischemic stroke. Researchers added a two-minute scan to the standard MRI for 274 adults admitted with stroke. They then compared the scan results to the patien…

This study looked at whether using ultrasound to guide a needle into the femoral artery (in the groin) helps doctors succeed on the first try in children. 149 children who needed this procedure for brain imaging or treatment took part. The goal was to see if ultrasound reduces th…

This study looked at 71 adults with suspected MVNT, a rare non-cancerous brain tumor. Researchers used special MRI scans to find unique patterns that help tell MVNT apart from other brain growths. The goal was to improve diagnosis, not to test a treatment.

This study looked at 20 adults who have a flat spot in the center of their retina (fovea plana) but no known albinism or vision problems. Researchers used eye scans and genetic tests to see if these people carry gene changes linked to albinism. The goal was to better understand w…

This study tested whether a technique called compressed sensing can speed up a specific type of brain MRI (QSM) without losing image quality. 82 people, including some with multiple sclerosis, had extra scan sequences added to their routine MRI. The goal was to see if the faster …

This study used a special eye scanner called SD-OCT to examine tiny granules in the retina of 20 healthy adults. Researchers wanted to see how these granules change with time and lighting. The goal was to better understand normal retinal structure, which could help future studies…

This study looked at how gadolinium, a dye used in MRI scans, changes the QSM signal in the brain's white matter. 73 patients with inflammatory central nervous system conditions had MRI scans before and after receiving gadolinium. The goal was to measure any differences in the si…

This study looked at eye problems in 23 COVID-19 patients in intensive care. Doctors checked for damage to the cornea, retina, and optic nerve at several time points. The goal was to find and treat eye issues early to prevent vision loss.

This study looked at whether a central monitoring station outside the operating room could safely replace having an anesthesia nurse in each room during eye surgeries like cataract removal. Researchers compared the rate of complications (like high blood pressure or low oxygen) be…

This study looked at eye damage in 34 people who were hospitalized for severe COVID-19. Researchers used many eye exams and scans to find problems like inflammation, dry eye, and blood vessel damage. The goal was to better understand what eye issues can happen after a serious COV…

This study looked at two ways of monitoring wet age-related macular degeneration (AMD) using eye scans: standard OCT B-scans and a newer technique called OCT angiography. The goal was to see if the newer scan could better detect when the disease is active, helping doctors decide …

This study looked at 51 adults who had COVID-19 2 to 12 months earlier and still had brain fog or other thinking problems. Researchers checked if the virus was still hiding in the nose's smell center. They compared these patients to a control group to see if lingering virus is li…

This study tested whether French versions of two standard hearing aid benefit questionnaires (IOI-HA and COSI) are accurate and reliable. Researchers enrolled 100 adults with hearing loss who use hearing aids. The goal was to confirm these questionnaires work well in French, so c…

This study aimed to create a database of heart rate and movement data from 13 adults with drug-resistant epilepsy. Participants wore a connected patch that recorded heart rate and motion, while also undergoing video-EEG monitoring to confirm when seizures occurred. The goal was t…

This study tested a new questionnaire designed to measure how well babies (0-36 months old) with eye diseases can see, even before they can talk. The goal was to help doctors decide the best time for surgery. The study included 150 children with different eye conditions and check…

This study used a special eye-imaging technique called adaptive optics to look at tiny blood vessels in the retina of people who recently had a stroke. Researchers compared these images to those from healthy individuals to see if the blood vessel structure differs. The goal was t…