Fondation Ophtalmologique Adolphe De Rothschild

This study compared two different eye scanning methods to monitor treatment for wet age-related macular degeneration. Researchers tested whether a newer scanning technique called OCT angiography could help doctors better time treatment injections compared to the standard OCT scan…

This study tested whether cooling the brain directly is more effective than cooling the whole body for protecting brain cells after a severe injury. It involved 41 adult patients in intensive care who had brain monitors and needed cooling for fever. Researchers compared keeping t…

This study tested whether giving the drug dornase alfa (Pulmozyme) during a standard clot-removal procedure could help more fully reopen blocked brain arteries in people with ischemic stroke. The goal was to see if adding this drug could improve blood flow to the brain beyond wha…

This study tested a procedure called thermocoagulation in children with severe, drug-resistant epilepsy. During a standard pre-surgery brain monitoring period, doctors applied tiny, precise heat burns to the specific brain area causing seizures. The goal was to see if this could …

This study tested which of two medical devices is better for quickly removing a blood clot from the brain after a major stroke. It compared a suction technique (ADAPT) against a more common stent retriever device. The goal was to see if the suction method could open blocked blood…

This study tested a wearable patch to see if it could automatically detect epileptic seizures. The patch tracked heart rate and body movement in 13 adults with epilepsy. Researchers compared the patch's data to hospital brain scans to train a computer program to recognize seizure…

This study aimed to find out which of two advanced types of 3 Tesla MRI brain scans is better at detecting active, inflamed lesions in people with multiple sclerosis (MS). Researchers compared two specific scanning techniques in 180 adults with MS who needed a brain scan for thei…

This study tested whether a special type of MRI scan could accurately identify a rare, non-cancerous brain tumor called MVNT. The goal was to help doctors make the right diagnosis without patients needing a risky surgical biopsy. Researchers enrolled 71 adults who showed signs of…

This study tested whether a special type of MRI scan could detect a common brain tumor called a meningioma using a much smaller dose of contrast dye. Researchers compared new scanning techniques using only one-sixth of the standard dye dose against the current best method in 514 …

This study tested whether new, high-resolution MRI scans could help doctors more accurately diagnose the cause of optic disc swelling. Optic disc swelling is a sign seen at the back of the eye that can be caused by many different eye or brain conditions. Researchers enrolled 197 …

This study tested a new questionnaire designed to help doctors understand how well babies and toddlers (under 3 years old) can see before they can talk. The goal is to give doctors better information to decide the best timing for eye surgery. Researchers compared answers from par…

This study tested two different types of specialized MRI brain scans to see which one is better at spotting a specific sign of multiple sclerosis (MS). Researchers compared the scans in 60 adults with recently diagnosed MS who were already getting an MRI as part of their regular …

This study tested a new artificial intelligence (AI) tool designed to help diagnose brain and nerve diseases from a simple picture of the back of the eye. Researchers used data from 693 patients with confirmed conditions like brain tumors, optic neuritis, and other optic nerve di…

This study tested whether a steroid nasal spray (budesonide) could help people regain their sense of smell after having COVID-19. It involved 120 adults who had lost their smell for at least 30 days after infection but had no other severe symptoms. The goal was to see if this com…

This small, exploratory study tested whether a device that stimulates the spinal cord could improve walking problems in people with Parkinson's disease. It involved five patients whose walking and 'freezing' episodes were not adequately controlled by their regular medications. Th…

This study aims to understand why some people have a specific, usually harmless, eye structure called fovea plana. Researchers will analyze the genes of 20 adults who have this condition but no vision problems or known albinism. The goal is to see if they carry genetic variations…

This study aimed to validate French translations of two standard questionnaires used to measure how much hearing aids help people. Researchers tested the questionnaires on 100 adults with hearing loss who use hearing aids. The goal was to ensure the French versions are reliable a…

This study aimed to see if a special, high-resolution eye scan could reveal details about tiny blood vessels in people who recently had a stroke. Researchers compared scans from 91 people—some with different types of stroke and some without—to look for patterns in vessel structur…

This study aimed to understand what eye problems develop in COVID-19 patients who are critically ill in the intensive care unit (ICU). Researchers examined the eyes of 23 patients at different times during their hospital stay to look for damage to the cornea, retina, and optic ne…

This study tested whether monitoring patients from a central station outside the operating room is as safe as having a dedicated anesthesia nurse in each room during common eye surgeries like cataract removal. Researchers compared the two methods across 900 patients to see if the…

This study aimed to understand what eye problems might develop in people who were hospitalized with severe COVID-19. Researchers examined 34 patients 4 to 6 months after they left the hospital, checking for any vision or eye health issues. The goal was to gather information, not …

This study used detailed MRI brain scans to learn more about central retinal artery occlusions, a sudden blockage in the eye's main artery that causes vision loss. Researchers scanned 63 adults who had just experienced this 'eye stroke' to look for specific signs on the images. T…

This study aimed to find out if using an ultrasound machine to guide the placement of a catheter in a child's leg artery is better than the standard method. It involved 149 children who needed this procedure for neurological treatments. Researchers compared how often doctors succ…

This study aimed to find the best way to measure blood pressure to predict dangerous bleeding in the brain after a stroke treatment. Researchers followed 455 stroke patients for 72 hours, comparing continuous monitoring with a finger device to standard cuff checks. The goal was t…

This study aimed to better understand a specific layer at the back of the eye, called the interdigitation area. Researchers used a high-tech eye scanner (SD-OCT) to take detailed pictures of this area in 20 healthy volunteers. They wanted to see if tiny granules they spotted in t…

This study tested whether new, faster MRI scanning techniques could produce images as good as standard, slower ones. It involved 82 adults who were already scheduled for a brain MRI. The research added up to 25 minutes of extra scanning time to compare different speed settings.

This study aimed to understand how a common MRI contrast dye called gadolinium affects specialized brain scan measurements. Researchers enrolled 73 adults with inflammatory brain conditions who were already scheduled for MRI scans with this dye. Participants underwent MRI scans b…

This study aimed to understand if the COVID-19 virus could persist in the lining of the nose (olfactory mucosa) in people suffering from long-term neurological symptoms like 'brain fog' after their initial infection. Researchers compared 51 adults who had COVID-19, some with last…