Could an eye exam reveal hidden brain damage in HIV patients?

NCT ID NCT02210130

Completed Knowledge-focused Sponsor: Fondation Ophtalmologique Adolphe de Rothschild Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study looks at cerebral small vessel disease (CSVD) — damage to tiny blood vessels in the brain that can cause memory loss and disability — in people with HIV over age 50. Researchers want to see if CSVD is linked to blood vessel problems in the eyes and kidneys, which could lead to simple screening tests. The study compares HIV patients with and without CSVD using brain scans, eye exams, and kidney tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to simple eye or kidney tests to screen for brain small vessel disease in people with HIV.
What could go wrong: This is an observational study, not a treatment trial. It may only confirm known links without providing new screening tools.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBRAL SMALL VESSELS DISEASE

Contacts and locations

Locations

Fondation Ophtalmologique Adolphe de Rothschild

Paris, Île-de-France Region, 75019, France

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