Fondation Ophtalmologique Adolphe De Rothschild

This study tests if injecting donor stem cells into the eye can help heal severe chemical burns and prevent blindness. About 21 adults with recent, serious eye burns will receive one or two stem cell injections. Researchers will check safety and whether the eye heals without a ho…

This study tests whether probenecid, a medicine used for gout, can stop cluster seizures in people with focal epilepsy. Participants are patients aged 6 to 50 who are in the hospital for presurgical monitoring and have their usual seizure medications paused to trigger seizures. T…

This study tests whether a guided breathing exercise called cardiac coherence can help people with claustrophobia complete an MRI scan with better image quality. About 220 patients aged 7 and older will be randomly assigned to either the breathing exercise or standard care (carto…

This study looks at whether adding dog-assisted therapy to standard psychomotor therapy can improve quality of life for adults with hard-to-treat epilepsy. Researchers will enroll 76 participants who will attend 10 sessions. The main goal is to see if their quality of life score …

This study will follow 2,000 people with multiple sclerosis (MS) for five years to understand why some get worse faster than others. Researchers will use brain scans, eye exams, blood tests, and activity monitors to track changes. The goal is to find factors—like inflammation, bl…

This study looks at immune activity in the brain of people who had a severe stroke and needed surgery to relieve pressure. Researchers will compare these patients to others having brain surgery for different reasons. The goal is to better understand the body's inflammatory respon…

This study looks at how the body's immune and inflammatory systems change in people having a stroke who receive clot-busting drugs or mechanical clot removal. Researchers will take blood samples at several time points over a year to measure inflammation markers. The goal is to se…

This study explores whether a special MRI technique called CEST can locate the brain area causing seizures in people with drug-resistant epilepsy. Researchers will scan 20 patients before surgery and compare the MRI results with standard methods. If it works, this could reduce th…

This study follows 100 children ages 4 to 8 who currently have perfect vision to see who develops nearsightedness (myopia) over 2 to 5 years. Researchers will track eye measurements and daily habits to uncover why some children become nearsighted while others don't. The goal is t…

This study looks at how often kidney problems occur in people with Wilson's disease, a rare genetic condition that causes copper buildup. Researchers will check 150 patients aged 7 and older for signs of kidney damage, including chronic kidney disease, tubule issues, and calcium …