Fondation Ophtalmologique Adolphe De Rothschild

This study tests whether probenecid, a medicine used for gout, can stop cluster seizures in people with focal epilepsy. Participants will be in the hospital for video-EEG monitoring while their usual seizure medications are reduced. The goal is to see if a single dose of probenec…

This study tests whether injecting donor stem cells into the eye can help heal severe chemical burns that often lead to blindness. About 21 adults with a recent serious eye burn will receive one or two stem cell shots. The goal is to prevent the eye from breaking open and to impr…

This study tests whether a guided breathing exercise called cardiac coherence can help people who are afraid of enclosed spaces complete an MRI scan without stopping early. About 220 patients aged 7 and older who report claustrophobia will be randomly assigned to either the breat…

This study tests whether adding dog-assisted therapy to standard psychomotor therapy can improve quality of life for adults with hard-to-treat epilepsy. Researchers will measure changes in quality of life, anxiety, and seizure frequency after 10 sessions. The goal is to see if in…

This study looks at how the immune system and inflammation change in people having a stroke who receive clot-busting treatment or mechanical clot removal. Researchers will measure inflammatory markers in the blood at several time points over a year. The goal is to see if these ma…

This study looks at immune system activity in the brain of people who have had a severe stroke and need surgery to remove part of the skull. Researchers will compare these patients to others having different types of brain surgery. The goal is to better understand inflammation af…

This study will follow 100 children aged 4 to 8 who currently have perfect vision to see who develops nearsightedness (myopia) over 2 to 5 years. Researchers will look at eye measurements and daily habits to identify early warning signs. The goal is to better understand why some …

This study looks at how often people with Wilson's disease have kidney problems. Wilson's disease causes copper buildup in the body, which can harm the kidneys directly or through complications. The study will check 150 patients aged 7 and older for signs of kidney damage, includ…

This study tests a new MRI method called CEST to measure brain chemicals (glutamate and glucose) in people with drug-resistant epilepsy who are candidates for surgery. The goal is to see if these chemical maps can better pinpoint the brain region causing seizures, potentially imp…