Assistance Publique - Hôpitaux De Paris
Clinical trials sponsored by Assistance Publique - Hôpitaux De Paris, explained in plain language.
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Growth hormone study for small babies checks diabetes risk
Disease control TerminatedThis study aimed to understand how growth hormone treatment affects children who were born small for their gestational age. Researchers compared two different dosing methods over two years to see which better promoted growth while minimizing risks like increased insulin resistanc…
Phase: PHASE4 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New hope to protect young lungs after Life-Saving transplants
Disease control TerminatedThis study tested whether a specific inhaled medication (a combination of fluticasone and salmeterol) could help improve lung function in children aged 6-17 who had received a stem cell transplant and were showing early signs of lung decline. The goal was to see if this treatment…
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New approach tested for severe pancreatitis from gallstones
Disease control TerminatedThis study tested whether using an early ultrasound scan (EUS) followed by a procedure to clear bile duct stones could help patients with severe gallstone pancreatitis recover better. It compared this early approach against standard conservative treatment. The trial was small and…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New tool aims to spot hidden hearing disorder in kids
Diagnosis TerminatedThis study aimed to create and test a new screening tool to help identify auditory processing disorder in children aged 7 to 13. The tool combines a questionnaire for parents and teachers with a short series of verbal and non-verbal hearing tests. The goal was to provide a faster…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Apr 01, 2026 23:26 UTC
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Scans vs scopes: which colon cancer test do patients prefer?
Diagnosis TerminatedThis study compared CT colonography (a special type of CT scan) to traditional colonoscopy for finding advanced polyps in people at high risk for colorectal cancer. Researchers wanted to see which test patients were more willing to complete and which was more effective at finding…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Mar 25, 2026 14:07 UTC
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Two-Drug combo tested to stop dangerous bleeding in new moms
Prevention TerminatedThis study tested whether giving two medications (oxytocin and misoprostol) together is better at preventing severe bleeding after a vaginal birth than giving oxytocin alone. It involved over 1,700 women who gave birth between 36 and 42 weeks of pregnancy. The goal was to see if …
Phase: PHASE4 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Prevention
Last updated Apr 01, 2026 14:43 UTC
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Breathing machine trial aims to shield kids from sickle Cell's worst lung attack
Prevention TerminatedThis study tested if a gentle breathing machine (non-invasive ventilation) could better prevent a dangerous lung problem called acute chest syndrome in children hospitalized for sickle cell pain crises. It compared the machine to the standard treatment of deep-breathing exercises…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Prevention
Last updated Mar 23, 2026 15:15 UTC
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Can a storyteller calm kids before surgery?
Symptom relief TerminatedThis small pilot study tested whether a special interactive storytelling device called LUNII could help reduce anxiety in young children before they had bone graft surgery for cleft lip and palate. Researchers wanted to see if using the device also helped with pain after surgery …
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Emergency room migraine breakthrough? anxiety drug tested for headache relief
Symptom relief TerminatedThis study tested whether adding clorazepate, a medication typically used for anxiety, to standard emergency room migraine treatment would provide better pain relief. The trial involved 323 adults with moderate to severe migraine attacks who came to the emergency room. Participan…
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Mar 12, 2026 13:51 UTC
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Researchers halt small study aimed at Fine-Tuning scleroderma treatment
Knowledge-focused TerminatedThis study aimed to find the best blood level of the drug mycophenolate mofetil (MMF) to treat skin thickening and lung problems in people with systemic sclerosis (scleroderma). It was an observational study that planned to follow patients for one year to see if specific drug lev…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Doctors map mystery of knee pain relief
Knowledge-focused TerminatedThis study aimed to better understand how a common pain-blocking injection for knee surgery works. Researchers used ultrasound imaging to see how often the numbing medicine spreads from its target area to other nerves behind the knee. The goal was to gather knowledge to potential…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Can a wearable alarm save seniors after a fall?
Knowledge-focused TerminatedThis study tested whether a wearable fall detection device helps seniors get help faster after a fall at home. Researchers compared 200 people over 75, with half wearing the alert device and half not, to see if it improved recovery or reduced hospital time. The goal was to learn …
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Tiny study halted early after tracking bone chemicals in myeloma
Knowledge-focused TerminatedThis study aimed to understand how certain chemicals in the blood and urine, which indicate bone health, change over time in older patients with multiple myeloma. The patients were receiving a standard intravenous medication to strengthen their bones. The study was terminated ear…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Do COVID vaccines work for people on Immune-Weakening drugs?
Knowledge-focused TerminatedThis study aimed to understand how well COVID-19 vaccines protect people with autoimmune or inflammatory diseases who take medications that weaken their immune system. Researchers compared the immune responses of 78 vaccinated patients on these drugs to those of healthy people. T…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists watch memories replay in sleeping minds
Knowledge-focused TerminatedThis study aimed to understand what happens in our minds during sleep by observing memory replay in real time. Researchers worked with 40 sleepwalkers, using sound cues during sleep to trigger specific learned movements. By watching sleepwalkers' physical responses to these cues,…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Can a video game train surgeons to fight prostate cancer?
Knowledge-focused TerminatedThis study aimed to see if an online video simulator helps surgeons learn a complex prostate cancer removal surgery. It compared surgeons trained with the simulator to those using standard training methods. The goal was to see if the simulator led to faster, safer surgeries with …
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Researchers track health risks in senior arthritis patients
Knowledge-focused TerminatedThis study aimed to understand how rheumatoid arthritis affects older adults differently than younger patients. Researchers compared two groups—patients over 65 and those under 50—tracking health problems like infections, cancers, heart issues, and fractures over five years. The …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Does rheumatoid arthritis make diabetes worse?
Knowledge-focused TerminatedThis study aimed to understand if having rheumatoid arthritis (RA) makes type 2 diabetes progress faster or become more severe compared to having osteoarthritis. Researchers compared 176 adults with both type 2 diabetes and either RA or osteoarthritis, tracking their need for new…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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Blood test could predict who wins against liver cancer
Knowledge-focused TerminatedThis study aimed to find a way to predict which patients with advanced liver cancer would benefit from a specific immunotherapy drug combination. Researchers planned to check patients' blood for certain immune cells before and after starting treatment to see if those cells could …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 12, 2026 13:50 UTC