Inhaler trial for Kids' lung decline after transplant ends early
NCT ID NCT04655508
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This phase 3 trial tested whether a combination inhaler (fluticasone and salmeterol) could improve lung function in children aged 6–17 who had a drop in breathing capacity after a stem cell transplant. The study aimed to prevent bronchiolitis obliterans, a serious lung complication. However, the trial was terminated early and enrolled only 35 participants, so firm conclusions cannot be drawn.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fluticasone propionate and salmeterol (Seretide inhaler)
- What this could lead to
- If it worked, this could help prevent a serious lung condition called bronchiolitis obliterans in children after stem cell transplant.
- What could go wrong
- The trial was terminated early and enrolled only 35 children, so results are limited. The treatment may not improve lung function or prevent disease progression.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BRONCHIOLITIS OBLITERANS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Houdouin véronique
Paris, 75019, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A gentle touch against coughs and colds: could manual therapy shorten respiratory illness?
- Can airway cell clues predict a rare lung disease in children?
- A bedtime kit for the hospital: can ear plugs and a lightbox help young transplant patients sleep?
- Human milk mouth care may shield preemies from lung infections
- New study aims to detect lung damage earlier in young transplant patients
- Can lung MRI replace CT scans for detecting a serious Post-Transplant lung condition?