Inhaler trial for Kids' lung decline after transplant ends early

NCT ID NCT04655508

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This phase 3 trial tested whether a combination inhaler (fluticasone and salmeterol) could improve lung function in children aged 6–17 who had a drop in breathing capacity after a stem cell transplant. The study aimed to prevent bronchiolitis obliterans, a serious lung complication. However, the trial was terminated early and enrolled only 35 participants, so firm conclusions cannot be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fluticasone propionate and salmeterol (Seretide inhaler)

What this could lead to

If it worked, this could help prevent a serious lung condition called bronchiolitis obliterans in children after stem cell transplant.

What could go wrong

The trial was terminated early and enrolled only 35 children, so results are limited. The treatment may not improve lung function or prevent disease progression.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans bronchiolitis obliterans syndrome disease related to hematopoietic stem cell transplant Respiration Disorders respiratory system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Houdouin véronique

    Paris, 75019, France