Drug combo aims to stop Post-Birth bleeding, but trial stopped early
NCT ID NCT01113229
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving two drugs—oxytocin and misoprostol—together could prevent postpartum hemorrhage (heavy bleeding) after vaginal birth better than oxytocin alone. The trial planned to include over 1,700 women giving birth at 36 to 42 weeks, but it was terminated early, so we don't have full results. The goal was to reduce the number of women losing more than 500 mL of blood within an hour of delivery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- oxytocin and misoprostol
- What this could lead to
- If it worked, this combination could offer a better way to prevent dangerous bleeding after childbirth, saving lives and reducing complications.
- What could go wrong
- The trial was terminated early, so results are incomplete. The combination may not be more effective than oxytocin alone and could carry added side effects like nausea or fever.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chi Poissy St Germain
Poissy, 78300, France