New stem cell method aims to protect kids with rare immune disease

NCT ID NCT02737384

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a way to improve stem cell transplants for children with combined immunodeficiency (CID), a condition where the immune system doesn't work properly. The approach removed certain naive cells from the donor stem cells to try to prevent graft-versus-host disease (a serious complication) while keeping the donor's memory T cells to fight infections. Only 4 children were enrolled before the study ended early, so results are limited.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Necker-Enfants Malades

    Paris, Paris, 75015, France