Breathing machine may prevent lung crisis in sickle cell kids

NCT ID NCT01501643

First seen Feb 15, 2026 · Last updated May 23, 2026 · Updated 14 times

Summary

This study tested whether a breathing machine (non-invasive ventilation) could prevent acute chest syndrome, a severe lung complication, in children with sickle cell disease who were hospitalized for severe pain and needed strong pain medicine. The standard prevention is deep-breathing exercises, but pain and sleep can make that hard. The study planned to compare the machine to the exercises, but it was stopped early after only 6 children enrolled.

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Contacts and locations

Locations

  • Hôpital Necker - Enfants Malades Hospital

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.