Could a new oral drug help teens with sickle cell pain?
NCT ID NCT05378555
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if oral ketamine can help control severe pain from sickle-cell crises in teens and young adults (ages 12–24). Participants receive the drug every 8 hours for 48 hours alongside standard pain care. The goal is to find better ways to manage pain and reduce the need for high-dose opioids.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for VASO-OCCLUSIVE CRISIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Breathing machine may ease lung risk for kids with sickle cell
- Could laughing gas replace opioids for sickle cell pain?
- Could pressurized oxygen ease sickle cell pain?
- New drug aims to cut sickle cell pain episodes
- New study aims to unlock secrets of sickle cell pain crises in kids
- Sickle cell drug inclacumab safety checked in long-term study