New hope for sickle cell pain: oral ketamine may reduce opioid need

NCT ID NCT05378555

First seen Nov 21, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This study explores whether oral ketamine can help control severe pain from sickle-cell crises in adolescents and young adults. Participants receive ketamine every 8 hours for 48 hours alongside standard pain care. The goal is to improve pain relief and reduce reliance on opioids and their side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.