Al-azhar University

This study tests whether using a special laser (810 nm diode) during repeat root canal treatment helps the bone around the tooth heal better. About 40 adults who need a second root canal on a single-root tooth will get either standard cleaning or standard cleaning plus laser disi…

This study looks at whether adding echinacea (Immulant®) to standard care can reduce symptoms and parasite levels in children aged 5–12 with weakened immune systems who have cryptosporidiosis, a diarrheal infection. About 60 children will take part. The goal is to see if the supp…

This study tests a new paste made from zinc oxide and ginger (6-gingerol) against a standard antibiotic paste for treating infected baby molars in children aged 4 to 8. The goal is to control the infection and save the tooth until it naturally falls out. Researchers will measure …

This study tests two nano-sized medications placed inside the tooth to control infection and inflammation after a root canal has failed. About 63 adults with a persistent tooth infection will receive either nano-calcium hydroxide or nano-chitosan. The goal is to see which better …

This study looks at how well a blood-filtering treatment called therapeutic plasma exchange works for people with autoimmune neurological diseases. Researchers will follow 60 patients in Egypt to see if their disability levels improve. The goal is to understand if this procedure …

This study tests whether giving ozone gas through the rectum can protect the brain and reduce damage in children who have suffered a brain injury from events like trauma, infection, or lack of oxygen. About 120 children from 1 month to 18 years old will receive the treatment whil…

This study tests whether coating a dental implant with erythropoietin gel helps it bond more firmly with the jawbone. Twenty-four adults needing a front tooth implant will be randomly assigned to get either a gel-coated or standard implant. The main goal is to measure implant sta…

This study tests two mouthwashes—one with probiotics (good bacteria) and one with ethyl lauroyl arginate—to see which better reduces cavity-causing bacteria, plaque, and acidity in the mouths of Egyptian children aged 6 to 12. Researchers will measure bacteria levels and plaque b…

This study tests a new type of cream that fizzes when applied, delivering the drug 5-fluorouracil deeper into the skin to help restore color in vitiligo patches. The trial involves 60 people with stable vitiligo who have not had treatment in the past 6 weeks. The main goal is to …

This study tests whether silver-hydroxyapatite nano-coated miniscrews work better than uncoated ones for moving the upper front teeth backward as a single unit. Fourteen teens aged 14-20 with Class I malocclusion and bimaxillary protrusion will be enrolled. The goal is to see if …

This study looks at two different types of dental files used during root canal treatment to see which one causes less pain during and after the procedure. About 56 adults with severe tooth pain in their upper premolars will be randomly assigned to one of the two file systems. The…

This study tests whether adding dexmedetomidine or tramadol to standard paracetamol can reduce bladder discomfort caused by urinary catheters after kidney stone surgery. About 60 adults aged 20–50 will be randomly assigned to one of three groups. The goal is to find a better way …

This study tests whether two different doses of oral melatonin can reduce anxiety in children before surgery. About 120 children aged 4 to 14 will receive either a low or high dose of melatonin before their operation. The goal is to see if melatonin can be a safer alternative to …

This study tests whether giving vitamin D3 locally and using a minor surgical technique called corticision can make orthodontic tooth movement faster. Sixteen patients aged 13-20 who need premolar extractions will be followed for 12 weeks. The goal is to see if these methods safe…

This study looks at whether applying vitamin C directly to the gums can safely reduce dark spots caused by natural pigmentation. Thirty adults with dark gums will receive vitamin C as a gel, with tiny needles (microneedling), or as injections (mesotherapy). The goal is to see whi…

This study looks at whether giving melatonin under the tongue before cataract surgery can reduce anxiety and help older adults relax. Sixty people aged 60 and older will receive either melatonin or a placebo. The goal is to find a safer alternative to standard sedatives that may …

This study tests three different ways to prevent pain from a tourniquet (a tight band that stops blood flow) during forearm surgery. Sixty adults having forearm surgery will be randomly assigned to receive one of three pain-blocking methods. The goal is to find which method works…

This study tests whether using a special laser along with standard ultrasonic cleaning can reduce pain and kill more bacteria after a root canal. About 120 adults with infected single-root teeth will be treated and asked to rate their pain. The goal is to find a better way to man…

This study tests if making small holes in the jawbone (micro-osteoperforations) helps move front teeth more safely and effectively in people with a deep bite. 18 participants aged 15-25 will receive standard braces with or without the extra procedure. The goal is to see if it red…

This study compares two methods of delivering a pain-relieving nerve block after a planned C-section. One method uses ultrasound to guide the injection, while the other uses the surgeon's view during the operation. The goal is to see which approach provides better pain control an…

This study tests if using a special laser to clean the tooth after a second root canal can lower pain and inflammation. About 52 adults with a failed first root canal and an infection at the tooth tip will be treated. The laser is used along with standard cleaning to see if it he…

This study looks at how changing the air pressure in a patient's lungs during a tummy tuck (abdominoplasty) affects their breathing after surgery. Researchers will measure lung pressure before and after the surgeon tightens the belly muscles, and then check lung function afterwar…

This study looks at how two types of dental crowns—stainless steel and bioflex—affect oral hygiene and bacteria in children aged 4 to 8. Researchers will measure the amount of a specific cavity-causing germ (S. mutans) and check gum health. The goal is to see which crown material…

This study observes 100 adults aged 20–40 who are having nose surgery (septorhinoplasty) to see if the length of time nasal packing is left in place affects the development of sore throat or pharyngitis. Participants will have their sore throat, swallowing difficulty, and throat …

This study looks at 20 adults with hearing loss in one ear but a normal-looking eardrum. Doctors want to see how often their best guess about the cause matches what they find during a small ear surgery. The goal is to improve diagnosis and treatment for this tricky condition.