ULCERATIVE COLITIS

This study is testing whether adding acupuncture to the standard medication mesalazine is better at controlling ulcerative colitis than the medication alone. It will involve 80 adults with mild-to-moderate active disease. Researchers will compare how well the combination reduces …

This study is testing whether an experimental drug called MK-8690 can help adults with moderate-to-severe ulcerative colitis. About 100 participants will receive either the drug or a placebo for 12 weeks to see if it reduces bowel inflammation and symptoms like frequent stools an…

This Canadian study is testing whether transferring healthy gut bacteria from donor stool (fecal transplant) can help control ulcerative colitis. Researchers will compare the transplant to a placebo in 85 adults with active disease to see if a larger trial is worthwhile. The goal…

This study is testing whether a rectal foam medication called budesonide can help control symptoms and bring about remission in children ages 5-17 with mild to moderate ulcerative colitis affecting the lower part of the colon. Researchers will compare two different doses of the f…

This study is gathering information to see how well hyperbaric oxygen therapy (HBOT) works for over 40 different health conditions. It will enroll about 100 people who have been referred for HBOT for conditions like Long COVID, Crohn's disease, and various ulcers. The main goal i…

This study is testing a medical device that filters harmful substances from the blood to help calm severe flare-ups of Crohn's disease and ulcerative colitis. It will compare patients receiving standard therapy alone to those receiving standard therapy plus the blood-filtering tr…

This study is testing a brief, one-day therapy workshop designed to help Veterans who have both inflammatory bowel disease (like Crohn's or colitis) and a mental health condition like depression or anxiety. The workshop uses acceptance and commitment therapy (ACT) to teach coping…

This study is testing a new self-management program designed to help people with active Crohn's disease or ulcerative colitis. Researchers want to see if teaching patients specific skills and behaviors can improve their quality of life and health outcomes. The main goal of this s…

This study is testing whether a 5-week program that teaches people to control their heart rate patterns can help reduce symptoms of ulcerative colitis. It will involve 23 adults who are currently experiencing a flare-up of their condition. The goal is to see if this non-drug tech…

This small pilot study is testing if an online sleep therapy program, specially adapted for people with ulcerative colitis (UC), can help improve their insomnia. Twenty adults with active UC and significant sleep problems will try the program, which involves five video visits and…

This study aims to learn if areas of bowel inflammation in people with Crohn's disease or ulcerative colitis are warmer than healthy tissue. During a standard colonoscopy, researchers will use a special temperature probe to measure heat inside the colon. The goal is to gather inf…

This study aims to understand the safety of the ulcerative colitis medication ozanimod when taken during pregnancy. It will follow pregnant women with UC who are taking ozanimod to see if it affects the health of the mother or the baby. The study is observational, meaning it coll…

This study aims to understand how doctors currently treat ulcerative colitis in real-world settings and whether switching to newer medications earlier leads to better long-term results. Researchers will analyze health records from 4,000 patients to track treatment patterns and ou…

This study aims to compare the risk of serious infections in older adults (65+) with Ulcerative Colitis or Crohn's Disease when they start different advanced medications. It will look back at the medical records of about 23,900 people on Medicare from 2016 to 2025 to see if one t…

This study aims to understand why children with ulcerative colitis are more likely to get serious C. difficile infections. Researchers will compare stool samples from 80 children across four groups: those with active colitis with and without the infection, those whose colitis is …