Amniotic cell secretions may fight gut inflammation and scarring — a lab study puts them to the test

This lab study tests whether a cell-free mixture of molecules and particles released by human amniotic mesenchymal stromal cells can reduce inflammation, prevent scarring, and promote healing in gut tissue from people with inflammatory bowel disease (Crohn's disease or ulcerative colitis). Researchers will expose tissue samples and immune cells from 40 patients to the secretome and measure changes in immune cells, inflammatory signals, and fibrosis markers. The goal is to see if this approach could one day lead to a new treatment for patients who do not respond well to current therapies.