New foam treatment could help kids with colitis avoid stronger drugs

NCT ID NCT05976802

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a steroid foam (budesonide) given rectally to children aged 5 to 17 with mild to moderate ulcerative colitis in the lower colon. The goal is to see if it can safely induce remission after 6 weeks of treatment. About 100 children will receive either a low dose, high dose, or placebo foam twice daily for 2 weeks, then once daily for 4 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

budesonide rectal foam

What this could lead to

If successful, this could provide a new treatment option for children with ulcerative colitis, helping them achieve remission without stronger medications.

What could go wrong

This is a phase 4 trial, but it's still early for this specific age group. The placebo group may also improve, and the foam may not work better than placebo. Side effects like irritation or infection are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••