ULCERATIVE COLITIS

This study tested an experimental oral medicine, PF-07054894, to see if it could help control ulcerative colitis. It involved 44 adults with mild to severe forms of the disease who hadn't responded well to standard treatments. The trial was terminated early, and its main goal was…

This study aimed to see if a medication called ursodeoxycholic acid (UDCA) could help control inflammation and improve quality of life for people with a condition called pouchitis. Pouchitis is a painful inflammation that can occur in patients who have had surgery for ulcerative …

This study aimed to see if a new drug called AVT16 works as well as the existing drug Entyvio for controlling moderate to severe ulcerative colitis. It involved about 300 adults and directly compared the two treatments over a year. The study was designed to be fair, with neither …

This study aimed to check the long-term safety and see if a drug called efavaleukin alfa could help control symptoms of moderate to severe ulcerative colitis over one to two years. It was for 25 people who had already completed a previous 52-week study with the drug. The trial ha…

This study tested VE202, a treatment made from specific live bacteria, in people with mild-to-moderate ulcerative colitis (UC). The goal was to see if changing the gut's bacterial community could safely reduce bowel inflammation and improve symptoms. The trial was terminated earl…

This study tested a new drug called efavaleukin alfa in adults with moderate to severe ulcerative colitis, a chronic bowel disease. The main goal was to see if the drug could help patients achieve remission, meaning their symptoms and bowel inflammation went away. The trial was d…

This study tested whether common cholesterol-lowering drugs called statins could help control ulcerative colitis by changing the mix of bacteria in the gut. It involved 177 adults with mild to moderate ulcerative colitis or Crohn's disease who were not already taking statins. The…

This study observed how well the approved drug tofacitinib worked for adults in Switzerland with moderate to severe ulcerative colitis. It aimed to gather real-world data on symptom control and gut inflammation by having patients complete questionnaires and use a home stool test.…

This study tested an experimental drug called vixarelimab in people with moderate to severe ulcerative colitis who hadn't responded well to other treatments. The trial aimed to see if the drug could reduce bowel inflammation and symptoms over 12 weeks, and then explore longer-ter…