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Pfizer's ulcerative colitis pill study halted early

NCT ID NCT05549323

Terminated Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental oral drug, PF-07054894, in adults aged 18-75 with mild to severe ulcerative colitis (UC). The goal was to see if the drug could safely help control the disease and reduce symptoms like diarrhea and rectal bleeding. The trial was terminated early, so results are limited. It was a Phase 1 study with 44 participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

inflammatory bowel disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ULCERATIVE COLITIS

Contacts and locations

Locations

  • Carta - Clinical Associates In Research Therapeutics Of America

    San Antonio, Texas, 78212, United States

  • Centrum Medyczne Med-Gastr

    Lodz, 91-034, Poland

  • Charité Research Organisation

    Berlin, 10117, Germany

  • Charité Universitaetsmedizin Berlin - Campus Mitte

    Berlin, 10117, Germany

  • GCP Clinical Research

    Tampa, Florida, 33609, United States

  • IHS Health Research

    Kissimmee, Florida, 34741, United States

  • IRMED

    Piotrkow Trybunalski, Łódź Voivodeship, 97-300, Poland

  • KLIMED Marek Klimkiewicz

    Bialystok, Podlaskie Voivodeship, 15-704, Poland

  • Kissimmee Endosocpy Center ( Endoscopy Only )

    Kissimmee, Florida, 34741, United States

  • MZ Badania Slowik Zymla Spolka Jawna

    Knurów, Silesian Voivodeship, 44-190, Poland

  • Medical Network Spółka z o.o. WIP Warsaw IBD Point Profesor Kierkuś

    Warsaw, Masovian Voivodeship, 04-501, Poland

  • NZOZ Centrum Medyczne KERmed

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-231, Poland

  • NZOZ Twoje Zdrowie EL Sp. z o. o.

    Elblag, Warmian-Masurian Voivodeship, 82-300, Poland

  • Orlando Diagnostic Center ( CXR Only )

    Kissimmee, Florida, 34741, United States

  • SP ZOZ Szpital Uniwersytecki w Krakowie

    Krakow, Lesser Poland Voivodeship, 30-688, Poland

  • Tampa Bay Endoscopy Center

    Tampa, Florida, 33603, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.