New drug shows promise for Long-Term control of ulcerative colitis

NCT ID NCT04277546

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the long-term safety of brazikumab, a drug given as a shot every 4 weeks, for people with moderate to severe ulcerative colitis. Participants had already taken part in an earlier study of brazikumab. The goal is to see if the drug remains safe over a longer period and to gather information for possible future approval.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

brazikumab

What this could lead to

If successful, this could provide a long-term treatment option for people with moderate to severe ulcerative colitis.

What could go wrong

This is an early-phase, small study focused on safety, not proof of cure. The drug may not work for everyone and could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Chula Vista, California, 91911, United States

  • Research Site

    Lancaster, California, 93534, United States

  • Research Site

    Colorado Springs, Colorado, 80907, United States

  • Research Site

    Lakeland, Florida, 33813, United States

  • Research Site

    Miami, Florida, 33165, United States

  • Research Site

    Miami Lakes, Florida, 33016, United States

  • Research Site

    Evansville, Indiana, 47715, United States

  • Research Site

    Beachwood, Ohio, 44122, United States

  • Research Site

    Oklahoma City, Oklahoma, 73112, United States

  • Research Site

    Humble, Texas, 77346, United States

  • Research Site

    České Budějovice, 370 01, Czechia

  • Research Site

    Ostrava, 702 00, Czechia

  • Research Site

    Hamburg, 20251, Germany

  • Research Site

    Kiel, 24105, Germany

  • Research Site

    Ulm, 89081, Germany

  • Research Site

    Haifa, 3109601, Israel

  • Research Site

    Jerusalem, 9103102, Israel

  • Research Site

    Milan, 20132, Italy

  • Research Site

    Rho, 20017, Italy

  • Research Site

    Roma, 00168, Italy

  • Research Site

    Kasama-shi, 309-1793, Japan

  • Research Site

    Kashiwa-shi, 277-0871, Japan

  • Research Site

    Minatoku, 108-8642, Japan

  • Research Site

    Krakow, 31-513, Poland

  • Research Site

    Rzeszów, 35-302, Poland

  • Research Site

    Sopot, 81-756, Poland

  • Research Site

    Torun, 87-100, Poland

  • Research Site

    Warsaw, 00-189, Poland

  • Research Site

    Warsaw, 03-580, Poland

  • Research Site

    San Juan, 00927, Puerto Rico

  • Research Site

    Cape Town, 7500, South Africa

  • Research Site

    Cape Town, 7708, South Africa

  • Research Site

    Plumstead, 7800, South Africa

  • Research Site

    Wŏnju, 26426, South Korea

  • Research Site

    Taichung, 40447, Taiwan

  • Research Site

    Taipei, 10002, Taiwan