Could a vitamin B3 pill help kids with colitis?
NCT ID NCT05561738
First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 2 times
Summary
This study tests whether a daily supplement called nicotinamide riboside (a form of vitamin B3) can help children with mild to moderate ulcerative colitis. About 40 kids will take either the supplement or a placebo for 6 to 12 months, alongside their usual treatment. The main goal is to see if such a study is practical, but researchers will also look at changes in gut cells and inflammation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Nicotinamide Riboside (a form of vitamin B3)
- What this could lead to
- If this works, it could point toward a new, simple supplement to help manage ulcerative colitis in children.
- What could go wrong
- This is a very early, small pilot study (40 people) focused on feasibility, not on proving the supplement works. It may show no benefit or have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224, United States
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