TRAUMATIC BRAIN INJURY

This study is testing whether a proven weight loss program can work just as well when delivered by video call to people who have had a moderate to severe traumatic brain injury (TBI). The goal is to make the program more accessible, especially for underserved groups. Researchers …

This study is testing whether certain already-approved medications can help people recover better after a traumatic brain injury (TBI). It will involve about 670 adults who recently suffered a moderate TBI. Researchers will compare recovery in people who receive the study drugs t…

This study is testing a weight loss program specifically designed for people who have had a moderate to severe traumatic brain injury. The program helps participants improve their eating habits and physical activity over 12 months, with follow-up checks at 18 months. Researchers …

This study is testing a special support program for people with traumatic brain injuries (TBI) who are about to be released from prison. The goal is to see if this program helps them adjust to life outside, find jobs, and avoid returning to prison. Researchers will compare 102 pa…

This study is testing whether an existing, FDA-approved drug can help people recover better from a severe traumatic brain injury (TBI). The drug is being used 'off-label,' meaning it's not yet approved for TBI. Researchers will compare recovery in a small group of 26 adults who r…

This study aimed to use advanced brain scanning to find the exact spots in the brain that cause seizures in people with hard-to-treat epilepsy. The goal was to create a better, non-invasive map to guide surgeons, potentially helping more people become seizure-free after surgery. …

This study is testing a new, faster type of magnetic brain stimulation to see if it can reduce persistent symptoms like brain fog and headaches after a concussion. Fifteen adults who have had symptoms for over three months will receive 30 short treatment sessions while researcher…

This study is testing a support program called BETTER for adults with traumatic brain injury (TBI) and their families after they leave the hospital. The program provides education, helps coordinate care, and teaches coping skills over 16 weeks to improve patients' quality of life…

This study is testing whether a safe, non-invasive brain stimulation technique can improve memory and thinking skills in veterans who had a mild traumatic brain injury over a year ago. Participants receive either real or fake (sham) stimulation on their scalp while doing memory t…

This study is testing whether fun virtual reality games in a shared online world (the metaverse) can help people with brain injuries or diseases like stroke, MS, or Parkinson's. The games focus on cooking, puzzles, and social activities to improve memory, attention, and thinking …

This small pilot study is testing whether adding virtual reality to treadmill training is a practical way to help people with traumatic brain injury. Researchers want to see if this approach can improve walking, balance, and confidence while reducing the fear of falling. The stud…

This study aims to see if a medication called pregnenolone can help improve symptoms for veterans with a history of chronic traumatic brain injury (TBI). It will compare pregnenolone to a placebo pill over 8 weeks to see if it eases psychological distress, pain, PTSD symptoms, an…

This study is testing whether a new therapy can help veterans with traumatic brain injuries improve their ability to tell stories and have meaningful conversations. Researchers are working with 34 veterans to see if this telehealth treatment is practical and acceptable to partici…

This study is testing a new teletherapy program called ICARE, designed to help people who have had a traumatic brain injury (TBI). The program aims to improve their ability to recognize others' emotions and show empathy, which can be challenging after a brain injury. The study in…

This study is testing whether a simple, at-home treatment using morning bright light can improve sleep for Veterans who have had a traumatic brain injury. Researchers also want to see if this light therapy helps with mood, thinking skills, and quality of life, and if they can fin…

This study aims to better understand the long-term effects of traumatic brain injury (TBI), particularly the risk of developing epilepsy afterward. Researchers are extending the follow-up of 300 people who were previously enrolled in a brain injury study to track their recovery a…

This study aims to understand why many people develop long-term thinking and memory problems after surviving a serious injury and ICU stay. Researchers are following 432 trauma patients to see how factors like confusion in the hospital (delirium) and body-wide inflammation affect…

This study aims to better understand and predict recovery for adults 65 and older who suffer a traumatic brain injury (TBI). Researchers will follow 1500 older adults who come to the emergency department with a head injury, along with some healthy comparison participants, for one…

This study aims to better understand what happens inside a child's brain after a severe head injury. Researchers will observe 50 children (ages 3-16) in intensive care by using special monitors to track brain pressure, oxygen levels, and chemical changes. The goal is to gather in…

This study is testing a web-based tool designed to help family members make difficult decisions about continuing or withdrawing life support for loved ones with severe brain injuries. The tool provides information and support to prepare families for conversations with doctors. Re…