Can a brain injury lead to epilepsy? new study aims to find out

NCT ID NCT05823766

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 300 people who had a traumatic brain injury (TBI) to learn more about the long-term risk of developing epilepsy. Researchers will use interviews, brain scans, blood tests, and EEGs to track changes over time. The goal is to better understand how and why epilepsy develops after a TBI, which could lead to better prediction and diagnosis in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could improve how doctors predict and diagnose epilepsy after a traumatic brain injury.

What could go wrong

This is an observational study, not a treatment trial. It will not directly test any new therapy, and results may take years to influence patient care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic post-traumatic epilepsy traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Spaulding Rehabilitation Hospital

    Charlestown, Massachusetts, 02129, United States

  • University of California, San Francisco

    San Francisco, California, 94110, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45267, United States

  • University of Pennsylvania/Penn Presbyterian Medical Center

    Philadelphia, Pennsylvania, 19104, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Texas Southwestern

    Dallas, Texas, 75390, United States

  • University of Texas at Austin

    Austin, Texas, 78712, United States

  • University of Washington

    Seattle, Washington, 98104, United States