Could common drugs help heal traumatic brain injuries? new trial aims to find out
NCT ID NCT05826912
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether certain FDA-approved drugs, used off-label, can help people recover better after a traumatic brain injury (TBI). About 672 adults with moderate to severe TBI will receive either an experimental drug or a placebo within 24 hours of their injury. The main goal is to see if the drugs improve functional recovery, measured by the Glasgow Outcome Scale, over three months.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Atrium Health Wake Forest Baptist
Charlotte, North Carolina, 28203, United States
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Indiana University Health
Indianapolis, Indiana, 46202, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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The University of Texas at Austin
Austin, Texas, 78712, United States
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UTHealth Houston
Houston, Texas, 77030, United States
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UW Health University Hospital
Madison, Wisconsin, 53792, United States
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University of California, San Francisco
San Francisco, California, 94110, United States
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University of Cincinnati Medical Center
Cincinnati, Ohio, 45219, United States
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University of Kentucky
Lexington, Kentucky, 40536, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States
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University of Utah
Salt Lake City, Utah, 84132, United States
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University of Washington
Seattle, Washington, 98104, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37203, United States
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Virginia Commonwealth University
Richmond, Virginia, 23298, United States