TINNITUS
Clinical trials for TINNITUS explained in plain language.
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Daily pill tested to halt hearing loss and quiet ringing ears
Disease control CompletedThis study tested a daily dietary supplement called ACEMg (Soundbites) to see if it could preserve or improve hearing and reduce symptoms of tinnitus (ringing in the ears) and hyperacusis (sound sensitivity). The 24-week at-home study involved 64 adults who self-reported hearing …
Matched conditions: TINNITUS
Phase: NA • Sponsor: Keep Hearing, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Scientists hunt for Tinnitus's 'Fingerprint' in the brain
Diagnosis CompletedThis study aimed to find a reliable, objective way to diagnose chronic tinnitus by measuring specific brain activity patterns. Researchers tested 560 people with and without tinnitus using EEG brain scans during listening tasks. The goal was to see if certain brain responses coul…
Matched conditions: TINNITUS
Sponsor: University of Regensburg • Aim: Diagnosis
Last updated Mar 30, 2026 14:34 UTC
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Scientists test 'Sound Bath' to quiet ringing ears
Symptom relief CompletedThis study tested whether short bursts of personalized sound could temporarily reduce the loudness of tinnitus, the perception of ringing or buzzing in the ears. Researchers worked with 45 adults who had chronic tinnitus to find the specific sound that best suppressed their sympt…
Matched conditions: TINNITUS
Phase: NA • Sponsor: University of Regensburg • Aim: Symptom relief
Last updated Apr 02, 2026 00:26 UTC
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AI 'Tinnitus Doctor' chatbot tested to ease ringing ears
Symptom relief CompletedThis study tested whether a 30-day program using an AI chatbot could help people manage chronic tinnitus, the perception of ringing or buzzing in the ears. 172 participants were randomly assigned to either use the interactive chatbot, which provided daily therapy-style conversati…
Matched conditions: TINNITUS
Phase: NA • Sponsor: Eye & ENT Hospital of Fudan University • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Could a simple ear clip quiet the ringing?
Symptom relief CompletedThis study tested whether a non-invasive vibrating device worn on the ear, combined with online mindfulness training, could reduce the severity and bother of chronic tinnitus. Forty adults with moderate to severe tinnitus were randomly assigned to use either the real device or a …
Matched conditions: TINNITUS
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Botox shots in ear muscles tested to quiet ringing
Symptom relief CompletedThis study tested whether injections of a medication similar to Botox (called Xeomin) into the small muscles around the ear could help reduce the bothersome ringing sound known as tinnitus. 41 adults with persistent tinnitus received either the real injection or a placebo (fake) …
Matched conditions: TINNITUS
Phase: PHASE2 • Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Zapping the ear to silence the ringing: new implant hope for tinnitus
Symptom relief CompletedThis Mayo Clinic study tested whether a small electrical stimulation to a part of the inner ear could provide short-term relief from severe, disruptive tinnitus (ringing in the ears). The 25 participants had severe, one-sided tinnitus that other treatments hadn't helped. The rese…
Matched conditions: TINNITUS
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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White noise wearable tested to quiet Veterans' ringing ears
Symptom relief CompletedThis small pilot study tested whether a non-invasive, wearable white noise device could help reduce the symptoms of tinnitus (ringing in the ears) and related mental health difficulties in military veterans. Twenty UK veterans with persistent tinnitus used the device for one mont…
Matched conditions: TINNITUS
Phase: NA • Sponsor: Combat Stress • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Experimental infusion tested to quiet ringing ears
Symptom relief CompletedThis small, completed study tested whether a single intravenous (IV) infusion of a drug called brexanolone was safe and could reduce symptoms for adults with tinnitus. Ten participants received a 6-hour infusion, and researchers measured changes in how loud and annoying their tin…
Matched conditions: TINNITUS
Phase: PHASE2 • Sponsor: Supernus Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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Herbal sleep aid tested for double trouble: insomnia and tinnitus
Symptom relief CompletedThis study tested whether a specific herbal formula could help adults who have both insomnia and tinnitus (ringing in the ears) and who did not want to take prescription sleeping pills. 108 participants were randomly assigned to take either a placebo (inactive pill), a low dose o…
Matched conditions: TINNITUS
Phase: NA • Sponsor: Dalin Tzu Chi General Hospital • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Zapping the brain with sound to quiet ringing ears
Symptom relief CompletedThis study tested a new non-invasive therapy for chronic tinnitus, the perception of ringing or buzzing in the ears. Researchers combined two techniques: gentle electrical brain stimulation (tRNS) and listening to white noise. The goal was to see if this combination could tempora…
Matched conditions: TINNITUS
Phase: NA • Sponsor: University of Zurich • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Could a psychiatric drug quiet ringing ears?
Symptom relief CompletedThis small, early-stage study tested whether olanzapine, a medication typically used for other conditions, could reduce the distress and perceived loudness of chronic tinnitus. Fifty adults with stable, long-term tinnitus tried the drug and a placebo in a random order. The main g…
Matched conditions: TINNITUS
Phase: PHASE1 • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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Hands-On therapy tested for ringing in the ears
Symptom relief CompletedThis study tested whether osteopathic treatment, a type of hands-on manual therapy, could reduce the annoyance and perceived loudness of tinnitus (ringing in the ears) for people whose symptoms are linked to neck, jaw, or muscle issues. Researchers compared eight weeks of real os…
Matched conditions: TINNITUS
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Symptom relief
Last updated Mar 23, 2026 15:19 UTC
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Sound waves target ear nerve in tinnitus trial
Symptom relief CompletedThis study tested a new, non-invasive ultrasound device called ZenBud, which aims to gently stimulate a nerve in the ear to potentially reduce tinnitus (ringing in the ears). Researchers wanted to see if people with tinnitus could tell the difference between real and fake treatme…
Matched conditions: TINNITUS
Phase: NA • Sponsor: University of Nottingham • Aim: Symptom relief
Last updated Mar 23, 2026 15:18 UTC
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Brain implant tested to silence severe ringing in ears
Symptom relief CompletedThis early study tested the safety and initial effectiveness of a new device surgically implanted to treat severe, chronic tinnitus (ringing in the ears). Nine adults with severe, long-term tinnitus that hadn't improved with other treatments participated. The goal was to see if t…
Matched conditions: TINNITUS
Phase: NA • Sponsor: Matthew L. Carlson, M.D. • Aim: Symptom relief
Last updated Mar 23, 2026 15:14 UTC
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Can an 8-Week online program quiet the ringing in your ears?
Symptom relief CompletedThis study tested two different 8-week online programs to help adults who are distressed by tinnitus, the perception of ringing or buzzing in the ears. Researchers compared an internet-based cognitive behavioral therapy (CBT) program, a mindfulness-based program, and a waiting li…
Matched conditions: TINNITUS
Phase: NA • Sponsor: Vilnius University • Aim: Symptom relief
Last updated Mar 18, 2026 14:40 UTC
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Brain-Tuned sound waves offer hope for ringing ears
Symptom relief CompletedThis study tested whether a specific pulsing sound pattern (40 Hz bursts) could provide longer-lasting relief from tinnitus compared to traditional continuous background noise. Researchers worked with 265 adults who experience chronic ringing in their ears to measure how strongly…
Matched conditions: TINNITUS
Phase: NA • Sponsor: Eye & ENT Hospital of Fudan University • Aim: Symptom relief
Last updated Mar 16, 2026 15:25 UTC
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Researchers dig through thousands of medical records to crack the code on ringing ears
Knowledge-focused CompletedThis study analyzed the medical records of over 3,300 people with tinnitus to learn more about its different forms. Researchers grouped patients by their type of tinnitus and looked for patterns in their health data. The goal is to create tools that help doctors better identify a…
Matched conditions: TINNITUS
Sponsor: Shanghai Jiao Tong University School of Medicine • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC