Can a One-Time infusion quiet the ringing? small study tests new approach

NCT ID NCT05645432

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 23 times

Summary

This early study tested a single 6-hour intravenous dose of brexanolone in 10 adults with tinnitus (ringing in the ears). The main goal was to check safety and tolerability, with a secondary look at whether the drug reduces perceived loudness. Results are not yet available, but the study provides initial data on this potential treatment.

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Contacts and locations

Locations

  • Sage Investigational Site

    Atlanta, Georgia, 30331, United States

  • Sage Investigational Site

    Iowa City, Iowa, 52242, United States

Conditions

Explore the condition pages connected to this study.