SMOKING
Clinical trials for SMOKING explained in plain language.
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Gift cards for good health: can rewards help native women kick the habit and shed pounds?
Disease control CompletedThis study tested whether giving rewards like gift cards can help Native American women quit smoking and lose weight. 125 women who smoked daily and were overweight or obese took part. They earned prizes for staying smoke-free and losing a half to one pound per week. The goal was…
Matched conditions: SMOKING
Phase: NA • Sponsor: Washington State University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New mobile program aims to help HIV-Positive veterans kick the habit
Disease control CompletedThis study tested a mobile phone-based wellness program (WISH) to help veterans with HIV quit smoking. 234 participants were split into two groups: one received the WISH program, the other got standard care (quitline and text support). The goal was to see if the wellness program …
Matched conditions: SMOKING
Phase: NA • Sponsor: Seattle Institute for Biomedical and Clinical Research • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Can text nudges help smokers with mental illness kick the habit?
Disease control CompletedThis pilot study tested a program called 'Nudges to Quit' that sends encouraging messages to people with serious mental illness who smoke. The goal was to see if these messages could help them start smoking cessation treatments like counseling or medication. The study involved 59…
Matched conditions: SMOKING
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Berry lozenges may shield Smokers' DNA
Disease control CompletedThis study looked at whether black raspberry lozenges could reduce DNA damage in mouth cells caused by smoking. 69 adult smokers took the lozenges for several weeks. The goal was to see if the berries could lower harmful chemical markers linked to oral cancer. Results may help fi…
Matched conditions: SMOKING
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Can peer support help public housing residents kick the habit?
Disease control CompletedThis study tested two approaches to help people living in public housing smoke less and reduce secondhand smoke. One approach offered one-on-one support to smokers to help them cut back or quit. The other aimed to get all residents in a building to support smoke-free rules. The s…
Matched conditions: SMOKING
Phase: NA • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Tailored smoking treatment shows promise for vulnerable patients
Disease control CompletedThis study tested a personalized approach to help people quit smoking by matching medication to their nicotine metabolism. 606 adults on Medicaid or Medicare who smoked daily took part. The goal was to see if tailoring treatment improves quit rates.
Matched conditions: SMOKING
Phase: PHASE3 • Sponsor: Vanderbilt-Ingram Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Phone therapy helps smokers kick the habit in national study
Disease control CompletedThis study tested a telephone program called Be Smoke Free that uses guided imagery (a relaxation technique) to help people stop smoking. Over 1,200 daily smokers from Arizona, New York, and West Virginia took part. Participants received coaching calls and were checked at 3 and 6…
Matched conditions: SMOKING
Phase: NA • Sponsor: University of Arizona • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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New combo treatment aims to help veterans quit smoking and manage PTSD
Disease control CompletedThis study tested a treatment called CPT-SMART that combines PTSD therapy, smoking cessation counseling, medication, and financial incentives to help veterans quit smoking. 120 veteran smokers with PTSD were randomly assigned to either the full program or a control group. The goa…
Matched conditions: SMOKING
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Laser boosts gum healing in smokers with deep pockets
Disease control CompletedThis study tested whether adding a diode laser to standard deep cleaning helps smokers with severe gum disease. 33 smokers were split into two groups: one got standard cleaning alone, the other got cleaning plus laser. After 3 months, the laser group had shallower gum pockets, le…
Matched conditions: SMOKING
Phase: NA • Sponsor: Selcuk University • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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New behavioral therapy shows promise for smoking cessation in HIV patients
Symptom relief CompletedThis study tested a new type of counseling called behavioral activation problem solving (BAPS) against standard smoking cessation counseling for people with HIV in Botswana. 651 participants were split into two groups to see which approach helped more people quit smoking. The goa…
Matched conditions: SMOKING
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Can a smartphone app help PTSD smokers kick the habit for good?
Symptom relief CompletedThis study tested whether a smartphone app could help people with PTSD quit smoking and avoid starting again. Participants received counseling, stop-smoking medications, and rewards for not smoking, plus the app. The goal was to see if the app made it easier to stay smoke-free co…
Matched conditions: SMOKING
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Cash for clean breath: new program helps homeless veterans quit smoking
Symptom relief CompletedThis study tested whether offering payments for low carbon monoxide readings can help homeless smokers quit. Twenty-five homeless Veterans received nicotine replacement therapy, counseling, and a mobile phone to record their breath tests. The goal was to see if this reward-based …
Matched conditions: SMOKING
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Hospital program helps caregivers kick the habit during Child's stay
Symptom relief CompletedThis study tested a smoking cessation program for caregivers of children admitted to American Family Children's Hospital. 23 caregivers received a 20-minute counseling session and used nicotine patches and lozenges for 2 weeks. The goal was to see if caregivers would use the prog…
Matched conditions: SMOKING
Phase: PHASE4 • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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New program aims to help lung cancer patients kick the habit
Symptom relief CompletedThis study tested a program to help lung cancer patients stop smoking and avoid starting again. 21 adults with lung cancer who smoked took part. The program included counseling, a web video, and support calls. The goal was to see if the program was easy to use and if patients lik…
Matched conditions: SMOKING
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Free samples of Quit-Smoking drugs mailed to your door: does it work?
Symptom relief CompletedThis study tested whether mailing free samples of varenicline (Chantix) or nicotine patches and lozenges helps smokers quit. 652 daily smokers were randomly assigned to receive a one-time sample of varenicline, nicotine replacement products, or no medication. Participants were no…
Matched conditions: SMOKING
Phase: PHASE1, PHASE2 • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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New program tackles smoking in HIV by easing anxiety and depression
Symptom relief CompletedThis study tested a 9-session program that uses cognitive-behavioral techniques to help people living with HIV quit smoking by reducing anxiety and depression. 131 daily smokers who were motivated to quit took part. The goal was to see if the program led to more people staying sm…
Matched conditions: SMOKING
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Hospital program aims to help teens kick vaping habit
Symptom relief CompletedThis study created and tested a program to help teens and young adults (ages 14-21) who vape or smoke quit while they are in the hospital. 144 participants took part, and the program focused on helping them stop for at least 30 days. The goal was to see if this hospital-based sup…
Matched conditions: SMOKING
Phase: NA • Sponsor: Children's Mercy Hospital Kansas City • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Can your phone help you quit smoking? new AR app shows promise
Symptom relief CompletedThis study tested a smartphone app that uses augmented reality to help reduce cravings to smoke. 14 adults who recently quit smoking tried the app and rated how easy it was to use and how much they liked it. The goal was to see if the app could be a helpful tool for quitting smok…
Matched conditions: SMOKING
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Virtual coach aims to help smokers kick the habit and move more
Symptom relief CompletedThis study tested a virtual coach delivered through a smartphone app to help adults quit smoking and increase physical activity. One hundred participants used the coach for about 16 weeks, with personalized chat conversations and exercises. The goal was to see if the program is f…
Matched conditions: SMOKING
Phase: NA • Sponsor: Leiden University Medical Center • Aim: Symptom relief
Last updated Jun 26, 2026 15:41 UTC
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Microaggressions linked to smoking urges in latinx study
Knowledge-focused CompletedThis study explored whether experiencing subtle racial slights (microaggressions) makes Latinx smokers want to smoke more or makes it harder to quit. Thirty daily smokers who identified as Hispanic or Latino took part. Researchers measured their smoking behavior, withdrawal sympt…
Matched conditions: SMOKING
Phase: NA • Sponsor: University of Houston • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Racial divide in smoking and stress: new study seeks answers
Knowledge-focused CompletedThis completed study examined how African American and white male smokers respond to stress and how that affects their smoking habits. Researchers used a psychological stress test and measured daily cortisol patterns to understand biological differences. The goal is to learn why …
Matched conditions: SMOKING
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Heated tobacco vs cigarettes: which is less harmful?
Knowledge-focused CompletedThis study looked at whether people who used a tobacco heating system for at least 2 years had lower levels of harmful chemicals, cell stress, and inflammation in their bodies compared to cigarette smokers. About 974 healthy adults aged 30-60 from Asia and Europe took part. The g…
Matched conditions: SMOKING
Sponsor: Philip Morris Products S.A. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Dental implant study reveals key factor in Long-Term bone loss
Knowledge-focused CompletedThis study looked at 142 people who had a sinus lift procedure using cow bone mineral before getting dental implants. Researchers measured how much bone was left around the implants years later, and checked if the original jawbone height, implant type, smoking, or diabetes played…
Matched conditions: SMOKING
Sponsor: Saint-Joseph University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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E-Hookah nicotine may damage blood vessels, small study suggests
Knowledge-focused CompletedThis study tested whether nicotine in electronic hookah (e-hookah) affects blood vessel function. Thirty-three healthy young adults who already used hookah or e-cigarettes vaped e-hookah with or without nicotine in separate sessions. Researchers measured blood vessel dilation and…
Matched conditions: SMOKING
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Flavored cigars may hook young smokers even more
Knowledge-focused CompletedThis study looked at whether little cigars and cigarillos (LCCs) are addictive, especially when flavored like fruit, and if addiction differs between men and women. Researchers studied 65 young adults aged 18-34 who smoke both LCCs and cigarettes. They measured how much people wo…
Matched conditions: SMOKING
Phase: NA • Sponsor: UConn Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Tabata workout may fight inflammation differently in smokers
Knowledge-focused CompletedThis study looked at how a short, intense workout called Tabata affects certain inflammation-related substances in the blood. Researchers compared 40 smokers and non-smokers to see if exercise changes these markers differently. The goal was to better understand how smoking and ex…
Matched conditions: SMOKING
Phase: NA • Sponsor: Ataturk University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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New nicotine pouches tested for addictiveness against cigarettes
Knowledge-focused CompletedThis completed study looked at whether six new nicotine oral products (pouches in flavors like cool mint and dragon fruit) are less addictive than regular cigarettes. Forty adult smokers tried each product in a controlled clinic setting. Researchers measured how much participants…
Matched conditions: SMOKING
Phase: NA • Sponsor: RAI Services Company • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Saliva test reveals smoking and gum disease worsen cell damage
Knowledge-focused CompletedThis study looked at whether smoking and severe gum disease (Stage III periodontitis) increase damage to DNA and RNA in cells. Researchers measured two markers of oxidative stress in saliva from 88 adults, including smokers and non-smokers with and without gum disease. They found…
Matched conditions: SMOKING
Sponsor: Zehra Hasgül • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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E-Cigarettes tested as a safer alternative for asthmatic smokers
Knowledge-focused CompletedThis study gave free e-cigarettes to 17 adult smokers with asthma for 8 weeks to see if they would smoke fewer regular cigarettes and have better lung function. Researchers measured changes in smoking habits, dependence, and asthma symptoms. The goal was to gather early informati…
Matched conditions: SMOKING
Phase: NA • Sponsor: Brown University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC