Saliva test reveals smoking and gum disease wreak havoc on your DNA

NCT ID NCT07279896

First seen Jan 07, 2026 · Last updated May 16, 2026 · Updated 23 times

Summary

This study looked at 88 adults to see if smoking and severe gum disease (Stage III periodontitis) cause damage to DNA and RNA. Researchers measured two markers of oxidative stress in saliva samples. They found that people with gum disease had more cell damage, and smokers with gum disease had the highest levels. The results suggest a simple saliva test could help detect gum disease and show how smoking harms cells.

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Contacts and locations

Locations

  • Ankara University Faculty of Dentistry, Department of Periodontology

    Ankara, Yenimahalle, 06560, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.