E-Hookah nicotine may damage blood vessels, small study suggests
NCT ID NCT04133376
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether nicotine in electronic hookah (e-hookah) affects blood vessel function. Thirty-three healthy young adults who already used hookah or e-cigarettes vaped e-hookah with or without nicotine in separate sessions. Researchers measured blood vessel dilation and other markers of vascular health before and after vaping. The goal was to see if nicotine alone causes the blood vessel damage seen with e-hookah use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
electronic hookah vaping with or without nicotine
What this could lead to
If successful, this could clarify whether nicotine in e-hookah harms blood vessels, helping guide future regulations or safer product design.
What could go wrong
This is a small, early-stage study (33 people) that only measures short-term effects. Results may not apply to long-term use or to older or less healthy people.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of California, Los Angeles
Los Angeles, California, 90024, United States