New nicotine pouches tested for addictiveness against cigarettes

NCT ID NCT06777784

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at whether six new nicotine oral products (pouches in flavors like cool mint and dragon fruit) are less addictive than regular cigarettes. Forty adult smokers tried each product in a controlled clinic setting. Researchers measured how much participants liked the products and how much nicotine entered their blood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nicotine oral products (cool mint, smooth, wintergreen, dragon fruit flavors; 6-15 mg nicotine) and Nicorette gum

What this could lead to

If successful, this could help understand whether these nicotine products have lower abuse potential than cigarettes, potentially guiding harm reduction strategies.

What could go wrong

This is a small, completed study in 40 smokers under controlled conditions. Results may not reflect real-world use or long-term effects, and the products still contain addictive nicotine.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nicotine dependence Smoking Tobacco Use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AMR Knoxville

    Knoxville, Tennessee, 37920, United States

  • AMR Lexington

    Lexington, Kentucky, 40509, United States