New nicotine pouches tested for addictiveness against cigarettes
NCT ID NCT06777784
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study looked at whether six new nicotine oral products (pouches in flavors like cool mint and dragon fruit) are less addictive than regular cigarettes. Forty adult smokers tried each product in a controlled clinic setting. Researchers measured how much participants liked the products and how much nicotine entered their blood.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- nicotine oral products (cool mint, smooth, wintergreen, dragon fruit flavors; 6-15 mg nicotine) and Nicorette gum
- What this could lead to
- If successful, this could help understand whether these nicotine products have lower abuse potential than cigarettes, potentially guiding harm reduction strategies.
- What could go wrong
- This is a small, completed study in 40 smokers under controlled conditions. Results may not reflect real-world use or long-term effects, and the products still contain addictive nicotine.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AMR Knoxville
Knoxville, Tennessee, 37920, United States
-
AMR Lexington
Lexington, Kentucky, 40509, United States
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