SMOKING

This study tests whether a daily kava drink can help active smokers (who don't plan to quit) smoke less and lower their risk of lung cancer. Twenty adults who smoke at least 5 cigarettes a day will take kava for 4 months. Researchers will check how well participants stick with th…

This study tests a special wellness program designed to help veterans living with HIV quit smoking. The program is compared to standard services like quitlines and text support. 226 veterans who smoke at least 5 cigarettes daily are taking part. The goal is to see if the tailored…

This study tests whether atorvastatin, a widely used cholesterol drug, can reduce lung inflammation and prevent flare-ups in 460 smokers with COPD. Participants will receive either the drug or a placebo for about a year. The goal is to see if statins can also lower the risk of lu…

This study tests whether an online training program helps people who recently quit smoking stay smoke-free and support others in their social network. About 940 adults who have been smoke-free for 2 to 8 weeks will take the training and be followed for 12 months. Researchers will…

This study tests a program called ENHANCE-TTS that trains pharmacists to help people living with HIV quit smoking. About 172 participants from six clinics will take part. The program gives pharmacists tools and support to offer smoking cessation counseling and medications. The go…

This study tests a proactive outreach program to help BIPOC adults who smoke quit tobacco. Researchers will use electronic health records to identify smokers and offer culturally tailored support, including counseling and medication. The goal is to reduce smoking rates and relate…

This study tests a program called ESCAPE, which combines smoking cessation support with education about lung cancer screening. It is for smokers aged 55-77 who have smoked heavily for years. The goal is to see if the program helps more people quit smoking and get screened for lun…

This study looks at whether switching completely from regular cigarettes to e-cigarettes can help cancer patients who refuse standard quitting methods. About 208 adults with cancer who smoke will be offered e-cigarettes and support to switch. The main goal is to see how many stop…

This study tests whether combining a special talk therapy for depression with standard smoking cessation help works better than standard help alone. About 91 adults with depression who smoke at least 5 cigarettes daily will take part. The goal is to see if this combined approach …

This study is testing a smartphone app designed to help people reduce or quit smoking. Participants use the app along with nicotine patches to see if the combination is helpful. The goal is to learn how easy the app is to use and whether it can support quitting. The study involve…

This study follows about 3,000 adults in Port-au-Prince, Haiti, for up to 7 years to track heart disease risks like high blood pressure, diabetes, and smoking. Researchers will measure how common these risks are and how they lead to heart attacks, strokes, or heart failure. The g…

This study looks at how Salvation Army staff can best help people who use tobacco learn about and connect with free services to quit smoking. About 233 adults who receive services at the Salvation Army will take part. Researchers will track how many people are referred to the Wis…

This study tests whether gentle reminders (nudges) to doctors, patients, or both can increase the number of people with HIV who smoke getting help to quit. About 500 patients and their doctors will be randomly assigned to receive different types of nudges or usual care. The goal …

This study tests whether smartwatches can detect changes in heart rate, breathing, and hand movements that happen before, during, and after smoking. Thirty adults who smoke will wear a smartwatch for three days at home and then visit a lab for monitoring. The goal is to find reli…

This study looks at how different tobacco products, like cigarettes, e-cigarettes, and smokeless tobacco, affect the way skin wounds heal. Researchers will measure skin temperature, blood flow, and signs of inflammation in 60 participants, including a non-smoking group. The goal …

This study tests a digital outreach strategy to help women who are at risk for lung cancer learn about screening options. Researchers will recruit 30 women aged 50-80 who smoke or recently quit and have had a normal mammogram. Participants receive emails and access to an online t…

This study looks at what helps people with head and neck or lung cancer stay away from cigarettes after they finish radiation treatment. Researchers will follow 100 patients for a year, checking in at 1, 6, and 12 months after treatment ends. The goal is to understand why some pe…

This study looks at how smokers with different reading skills respond to health messages about smoking risks. About 500 smokers listened to recorded messages that varied in emotion and focus (benefits of quitting vs. risks of not quitting). The goal is to see which message types …

This study looks at how to help VA medical centers offer virtual programs that prevent heart disease, diabetes, and depression in women Veterans. It involves 20 VA sites across 4 regions, not individual patients. The goal is to see which strategies work best to get women to sign …

This study tests whether giving doctors and patients a personalized risk report (based on clinical or genetic info) increases lung cancer screening and smoking cessation. About 915 patients and their primary care doctors are taking part. The goal is to see if tailored feedback he…