SMOKING

This study tested whether adding a special type of talk therapy (CBASP) to standard smoking cessation treatment helps depressed smokers quit and feel better. About 91 adults with depression who smoked at least 5 cigarettes a day took part. The goal was to see if the combined appr…

This study tests whether taking progesterone pills can prevent new mothers from relapsing into cigarette smoking after childbirth. Researchers will enroll 171 women who recently quit smoking during pregnancy to see if the hormone helps them stay smoke-free and reduces secondhand …

This study looks at whether sending reminders (nudges) to doctors, patients, or both can increase the number of people with HIV who smoke getting help to quit. About 500 patients and their doctors are involved. The goal is to see if these nudges lead to more referrals and partici…

This study looks at whether giving e-cigarettes to cancer patients who smoke—and who have turned down standard quitting help—can help them switch away from regular cigarettes. About 208 adults with cancer will either receive an e-cigarette and support to switch, or standard care …

This study tests whether atorvastatin, a widely used cholesterol medication, can reduce inflammation and prevent flare-ups in smokers with chronic obstructive pulmonary disease (COPD). About 460 participants will receive either atorvastatin or a placebo for several months. The go…

This study tests whether an online training program helps people who recently quit smoking stay smoke-free and also support others in their social network to quit. About 940 adults who have been smoke-free for 2 to 8 weeks will take part. They will complete online surveys and pro…

This study tests a proactive, culturally tailored outreach program to help BIPOC adults who smoke quit tobacco. Researchers will enroll 700 participants from two health systems and provide personalized materials and support to connect them with proven cessation treatments. The go…

This study tests whether a daily kava drink can help active smokers who don't plan to quit reduce their smoking and lower their risk of lung cancer. Twenty adult smokers will take kava daily for several months. Researchers will check how well participants stick with the regimen, …

This study tests a program called ESCAPE that combines counseling, nicotine replacement, digital videos, and lung screening education to help high-risk smokers quit. It involves 153 smokers aged 55-77 with a heavy smoking history. The program is compared to standard care (brief a…

This study is testing whether a smartphone app, combined with nicotine patches, can help people reduce or quit smoking. The app guides users to smoke on a schedule and tracks their progress. The study involves 56 adult smokers who smoke at least 10 cigarettes a day. The goal is t…

This study tests whether off-the-shelf smartwatches can detect changes in heart rate, breathing, and hand movements before, during, and after smoking. Thirty adults who smoke will wear the devices at home and in a lab setting. The goal is to find reliable signals that could one d…

This study looks at how Salvation Army staff can help people who smoke learn about and use free quit-smoking services, like the Wisconsin Tobacco Quit Line. Researchers will train staff to offer a short survey that gives feedback on smoking risks and treatment options. The goal i…

This study tests a digital outreach strategy to help women who are at risk for lung cancer learn about screening. Researchers will contact women ages 50-80 who smoke or recently quit and had a normal mammogram. The goal is to see if emails and a web tool called LungTalk can incre…

This study tests a program called ENHANCE-TTS that trains pharmacists at HIV clinics to provide tobacco treatment. Researchers will see if the program helps pharmacists offer more smoking cessation services and if it helps patients quit. About 172 people from six clinics will tak…

This study follows 100 head and neck or lung cancer patients who are current or former smokers and receive radiation therapy. Researchers track who stays smoke-free at 1, 6, and 12 months after treatment ends, and what factors help or hinder abstinence. The goal is to learn how t…

This study looks at how to help VA medical centers offer virtual programs that prevent heart disease, diabetes, and depression in women Veterans. Researchers are testing two different support strategies at 20 VA sites to see which works better. The study does not involve patients…

This study looks at how different tobacco products, like cigarettes, e-cigarettes, and smokeless tobacco, affect the way skin wounds heal. Researchers will measure skin temperature, blood flow, and signs of inflammation in 60 participants, including a non-smoking group. The goal …

This study follows about 3,000 adults in Port-au-Prince, Haiti, to learn how common heart disease risk factors like high blood pressure, diabetes, and smoking are, and how they lead to heart attacks, strokes, and other heart problems. Researchers will track participants for about…

This study looks at how smokers with different reading skills respond to various health messages about smoking risks. About 494 smokers will listen to and read messages that are either factual or emotional, and either highlight benefits of quitting or costs of not quitting. The g…

This study tests whether giving smokers and former smokers a personalized risk report (based on clinical and genetic factors) helps doctors order lung cancer screening and helps patients follow through. About 915 participants will be randomly assigned to usual care or one of two …