New combo therapy aims to help depressed smokers kick the habit

NCT ID NCT00494728

First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 35 times

Summary

This study tests whether adding a special type of talk therapy (CBASP) to standard smoking cessation treatment helps depressed smokers quit and stay smoke-free. About 91 adults with depression who smoke at least 5 cigarettes daily will be randomly assigned to either the CBASP combo or a health education combo. Researchers will track quit rates, mood changes, and brain responses over 6 months.

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Contacts and locations

Locations

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.