Can a smartphone program help heavy smokers quit and get lifesaving scans?

NCT ID NCT04691297

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a program called ESCAPE that combines counseling, nicotine replacement, digital videos, and lung screening education to help high-risk smokers quit. It involves 153 smokers aged 55-77 with a heavy smoking history. The program is compared to standard care (brief advice and a quitline referral). The goal is to see if the digital approach leads to more people quitting and getting screened for lung cancer.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
behavioral counseling, nicotine replacement therapy, digital storytelling videos, and lung screening education
What this could lead to
If successful, this program could help high-risk smokers quit more effectively and increase lung cancer screening rates, potentially reducing lung cancer deaths.
What could go wrong
This is a small Phase II trial with only 153 participants, so results may not apply to everyone. The program's success depends on participants engaging with digital tools, which may not work for all.

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Conditions

The condition(s) this trial relates to.

Smoking Smoking Cessation Tobacco Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

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