SKIN CANCER

This early-stage trial is testing a new oral drug called KESONOTIDE in people with advanced solid tumors that have spread. The main goal is to find a safe dose and see how well the body handles the medicine. About 80 adults with cancers like prostate, breast, lung, ovarian, and o…

This study is testing a non-surgical treatment for common skin cancers like basal cell and squamous cell carcinoma. Researchers are using fractional lasers on the cancer spots, followed by a prescription ointment applied for five nights. The goal is to effectively treat the cance…

This study is testing whether adding high-intensity exercise and a high-fiber diet to standard immunotherapy can improve health outcomes for people with advanced melanoma. Researchers want to see if these lifestyle changes are doable during treatment and if they can improve gut h…

This Canadian study is testing whether a personalized approach to cancer treatment works. It gives the immunotherapy drug atezolizumab to about 200 patients with advanced breast, lung, or other cancers, but only if their tumor's genetic analysis suggests they might respond. The g…

This study is testing a new oral medication called Alintegimod, given alongside the immunotherapy drugs ipilimumab and nivolumab. It aims to see if this combination is safe and can help control advanced cancers that have spread or returned after other treatments. The study will e…

This study is testing a new cancer treatment that places tiny radioactive seeds directly into tumors. It is for adults with certain skin, mouth, or soft tissue cancers that are near the surface. Researchers will check if the treatment safely shrinks the tumors and improves patien…

This study is testing a new support program for cancer survivors who struggle to afford or access healthy food. Researchers will compare 100 patients who receive help from a patient navigator to those getting standard care, to see if the program improves food security, diet quali…

This study is testing if freezing one growing tumor (cryoablation) while giving two immunotherapy drugs (ipilimumab and nivolumab) can help control advanced melanoma that has continued to grow despite prior immunotherapy. It aims to see if this combination is safe and effective f…

This is a first-in-human study to find a safe and effective dose of a new drug called ONM-501. The drug is injected directly into tumors and is being tested alone and in combination with an approved immunotherapy drug (cemiplimab) in adults with advanced cancers that have stopped…

This study is looking at how well immunotherapy drugs work for people in Slovenia with advanced melanoma that has spread. It will follow 100 adults receiving these drugs as their first treatment. Researchers also want to see if measuring a specific protein (PD-L1) in the tumor or…

This study is testing a new combination treatment for people with advanced head and neck cancer that has come back or spread. Doctors will place tiny, temporary radioactive seeds directly into the tumor to deliver a high dose of radiation, while patients also receive a standard i…

This study is testing a personalized treatment for people with advanced forms of skin cancer (cutaneous squamous cell carcinoma or Merkel cell carcinoma) that have come back after standard immunotherapy. Doctors take a patient's own immune cells from a tumor, grow large numbers o…

This study is testing a new AI tool called Dermalyser that helps primary care doctors decide if a skin spot might be cancer. About 30 clinics across five countries will either use the AI tool or their standard exam methods. The goal is to see if the AI helps catch more cancers ea…

This study is testing a new diagnostic platform that uses artificial intelligence to analyze small pieces of a patient's tumor. The goal is to predict whether a patient's cancer will respond to immunotherapy drugs before they start treatment. Researchers will compare the AI's pre…

This small, early study is checking if it's safe and practical to give vitamin A and a form of vitamin B3 (nicotinamide) to kidney transplant patients who have had skin cancer. The goal is to see if these vitamins change levels in the blood and gather information for a future, la…

This study aims to see if different ways of telling people about their personal skin cancer risk can encourage them to adopt better sun safety habits. It will enroll 2,900 adults from community health centers who have recently tanned or gotten sunburned. Researchers will track ch…

This study aims to find a better way to manage pain after Mohs surgery, a common procedure for skin cancer. Researchers are comparing three different pain relief plans, including a medication called meloxicam, to see which one works best. About 300 adults having this surgery will…

This study collects tumor tissue samples from cancer patients to research whether laboratory tests can predict which patients will respond to immunotherapy drugs. Researchers will analyze how live tumor samples react to immunotherapy treatments in the lab, then compare those resu…

This study is testing a blood test that looks for tiny pieces of tumor DNA to see if it can detect cancer recurrence earlier than standard scans. It aims to enroll 100 adults, including people with various solid tumors and healthy volunteers. The goal is to gather information tha…

This study aims to find blood markers that might help predict how skin cancer will progress and respond to treatment. Researchers will collect blood samples from 20 adults with melanoma or other skin cancers who are undergoing regular treatment. The goal is to see if certain subs…

This early-phase study is testing if injecting a standard flu vaccine directly into a type of skin cancer tumor can change the immune cells inside it. Researchers will study the tumor tissue from 25 participants after this injection and their standard surgery to see if the vaccin…

This study is building a large, long-term database of health information and biological samples from people with cancer, people at risk for cancer, and healthy volunteers. The goal is to collect this data to help researchers better understand what causes cancer and how to prevent…

This study aims to understand how a local treatment called electrochemotherapy changes the environment inside and around melanoma skin tumors. Researchers will treat patients who have melanoma that has spread to the skin and take small tissue samples before and after treatment. B…