Freezing tumors may boost immunotherapy in stubborn melanoma

NCT ID NCT05779423

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 25 times

Summary

This study tests if freezing part of a growing tumor (cryoablation) combined with two immunotherapy drugs (ipilimumab and nivolumab) can help control advanced melanoma that stopped responding to prior treatment. About 37 adults with unresectable melanoma will receive the combination. The goal is to see if this approach shrinks tumors or stops them from growing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital Cancer Center

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.