Flu vaccine injected into skin tumors: a new cancer weapon?

NCT ID NCT06664151

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing whether injecting the seasonal flu vaccine directly into skin cancer tumors can boost the immune system's attack on the cancer. About 25 people with cutaneous squamous cell carcinoma will receive one injection into their tumor before standard surgery. Researchers will measure changes in immune cells inside the tumor to see if the vaccine helps fight the cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fluzone Trivalent (influenza vaccine, flu shot)

What this could lead to

If it works, this could point toward a new way to use existing vaccines to help the immune system fight skin cancer.

What could go wrong

This is a very early, small trial (25 people) testing a concept, not a treatment. It may show no immune benefit or cause side effects like injection-site reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

skin cancer skin neoplasm skin squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact