CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
Clinical trials for CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC) explained in plain language.
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Could a shot replace the knife for skin cancer?
Disease control Recruiting nowThis phase 3 trial tests whether injecting the drug cemiplimab directly into early-stage skin cancer tumors can work as well as surgery. About 369 people with small tumors on the head, neck, hand, or shin will be randomly assigned to get either the injections or standard surgery.…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
Phase: PHASE3 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jul 01, 2026 23:00 UTC
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Could a 2-Week radiation course replace longer treatment for skin cancer?
Disease control Recruiting nowThis study tests whether a short course of radiation (5 treatments over 2 weeks) can prevent cancer from coming back in people with high-risk head and neck skin cancer after surgery. For those with moderate-risk cancer, researchers want to see if simply monitoring them closely is…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
Phase: PHASE2 • Sponsor: University of Vermont Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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New drug KUP-101A enters first human tests for advanced skin cancers
Disease control Recruiting nowThis early-stage study tests a new drug called KUP-101A in 21 people with advanced skin cancers (like melanoma or Merkel cell carcinoma) that have not responded to other treatments. The main goals are to find the safest dose and check for side effects. Researchers will also measu…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
Phase: PHASE1 • Sponsor: Kupando GmbH • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Radiation or watchful waiting? new trial for aggressive skin cancer
Disease control Recruiting nowThis phase 3 trial compares two strategies for people with high-risk cutaneous squamous cell carcinoma after surgery: adding radiation therapy versus simply monitoring. About 266 participants will be randomly assigned to one of the two groups and followed for at least two years. …
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
Phase: PHASE3 • Sponsor: Centre Leon Berard • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Experimental virus therapy takes on advanced cancers in first human trial
Disease control Recruiting nowThis early-stage trial is testing a new treatment called VET3-TGI, a virus designed to infect and destroy cancer cells. It is being given alone or with the immunotherapy drug atezolizumab to 60 people with advanced solid tumors that have not responded to standard treatments. The …
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
Phase: PHASE1 • Sponsor: KaliVir Immunotherapeutics • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Simple cream may shield transplant patients from skin cancer
Prevention Recruiting nowThis study tests whether a daily application of 5% niacinamide cream can prevent skin cancer in organ transplant recipients, who are at high risk due to long-term immune-suppressing drugs. Twenty adult transplant recipients with a history of precancerous skin spots and at least o…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
Phase: EARLY_PHASE1 • Sponsor: Marissa Lobl • Aim: Prevention
Last updated Jun 27, 2026 13:03 UTC
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French study tracks Real-World skin cancer care for 1500 patients
Knowledge-focused Recruiting nowThis study follows 1,500 French patients with advanced cutaneous squamous cell carcinoma (a type of skin cancer) who need systemic treatment (medication that works throughout the body). Researchers will collect information from medical records and ongoing visits to see how treatm…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Blood test may spot head and neck Cancer's return
Knowledge-focused Recruiting nowThis study looks at whether a blood test that finds tumor DNA can predict if head and neck cancer comes back after treatment. About 250 adults who have finished curative treatment will give blood samples over time. The goal is to see if a positive test result matches cancer relap…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Flu vaccine injected into skin tumors: a new cancer weapon?
Knowledge-focused Recruiting nowThis early-phase trial is testing whether injecting the seasonal flu vaccine directly into skin cancer tumors can boost the immune system's attack on the cancer. About 25 people with cutaneous squamous cell carcinoma will receive one injection into their tumor before standard sur…
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
Phase: EARLY_PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Can a simple blood test predict immunotherapy success in skin cancer?
Knowledge-focused Recruiting nowThis study is enrolling 30 people with a common skin cancer called cutaneous squamous cell carcinoma who are about to start treatment with the immunotherapy drug cemiplimab. Researchers will use advanced lab techniques to analyze immune cells and molecules in participants' blood …
Matched conditions: CUTANEOUS SQUAMOUS CELL CARCINOMA (CSCC)
Sponsor: Instituto de Investigación Biomédica de Salamanca • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:53 UTC