Alpha radiation seeds target tumors from the inside

NCT ID NCT04534127

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a device called DaRT that delivers a unique type of radiation (alpha particles) directly into tumors. It is designed for people with certain skin cancers, mouth cancers, or soft tissue sarcomas that are accessible for direct injection. The goal is to see if this approach can shrink or control tumors while being safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Diffusing Alpha Radiation Emitters Therapy (DaRT) device

What this could lead to

If effective, this approach could offer a new, targeted treatment option for certain skin, mouth, and soft tissue cancers without the need for surgery or systemic therapy.

What could go wrong

This is an early study with a small number of participants, so results may not apply to all patients. The treatment involves inserting radioactive seeds into tumors, which carries risks like infection, pain, or incomplete tumor coverage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

basal cell carcinoma Kaposi's sarcoma lip cancer oral cavity neoplasm skin cancer skin neoplasm soft tissue neoplasm Soft Tissue Neoplasms soft tissue sarcoma squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck tongue cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sharett institute, Hadassah Medical Center - Ein-Kerem

    RECRUITING

    Jerusalem, 91120, Israel

    Contact