Alpha radiation seeds target tumors from the inside
NCT ID NCT04534127
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a device called DaRT that delivers a unique type of radiation (alpha particles) directly into tumors. It is designed for people with certain skin cancers, mouth cancers, or soft tissue sarcomas that are accessible for direct injection. The goal is to see if this approach can shrink or control tumors while being safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Diffusing Alpha Radiation Emitters Therapy (DaRT) device
- What this could lead to
- If effective, this approach could offer a new, targeted treatment option for certain skin, mouth, and soft tissue cancers without the need for surgery or systemic therapy.
- What could go wrong
- This is an early study with a small number of participants, so results may not apply to all patients. The treatment involves inserting radioactive seeds into tumors, which carries risks like infection, pain, or incomplete tumor coverage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sharett institute, Hadassah Medical Center - Ein-Kerem
RECRUITINGJerusalem, 91120, Israel
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