RHEUMATOID ARTHRITIS

This study tested a new drug called IHL-675A in people with rheumatoid arthritis to see if it safely reduces pain and improves daily function. About 20 volunteers took either IHL-675A, CBD, hydroxychloroquine, or a placebo twice daily for 24 weeks. The study was stopped early, so…

This study followed 60 adults with rheumatoid arthritis in Colombia to see how well they stuck to their etanercept injections using a smart device called Smartclic. Researchers checked medical records and pharmacy data over 40 weeks to measure adherence, disease activity, and phy…

This study looked at how well the Cadence Total Ankle System works over time for people with severe ankle arthritis. Researchers followed 61 patients who had ankle replacement surgery to see how long the implant lasted and if it improved movement and daily function. The study was…

This study looked at whether using a smartphone app and a hand-strength device could help people with rheumatoid arthritis manage their condition with fewer in-person doctor visits. The goal was to see if remote monitoring could reduce the number of consultations needed over six …

This study tested whether adding a 12-week course of VIB4920 to standard TNF-inhibitor therapy could improve disease control in people with rheumatoid arthritis who did not respond well to TNF-inhibitors alone. Only 2 participants were enrolled before the study was stopped. The g…

This study tested a drug called peresolimab in 491 adults with moderate-to-severe rheumatoid arthritis, a condition causing painful, swollen joints. The goal was to see if the drug safely reduces symptoms like joint tenderness and swelling compared to a placebo. The trial was sto…

This study looked at whether small fluid-filled sacs between the foot bones, called intermetatarsal bursitis, cause pain in people with rheumatoid arthritis. Only 3 patients were enrolled before the study ended early. Researchers used MRI and ultrasound to find these sacs and tra…

This study looked at special immune cells called regulatory T cells in the joint fluid of 19 people with rheumatoid arthritis during a flare-up. The goal was to understand how these cells behave in the inflamed joint compared to the blood. No treatment was given; the study was st…

This study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also take daily aspirin for heart health. Eight adults with arthritis and increased heart risk took each pain reliever for …

This study aimed to understand if older adults with rheumatoid arthritis face more serious health issues like infections, cancer, heart disease, and bone fractures compared to younger patients. Researchers planned to follow 176 participants, but the study was stopped early. The g…

This study looked at whether JAK inhibitors, a type of drug for rheumatoid arthritis, can boost the anti-inflammatory activity of certain immune cells called B cells. Researchers tested this in lab experiments using blood samples from 27 adults with rheumatoid arthritis. The goal…

This study aimed to see if pairing rheumatoid arthritis patients for one-on-one support could improve their health and understanding of the disease. About 65 adults with RA were to be matched with a buddy. The study was terminated early, so results are limited.

This study looked at whether immunosuppressive medications used for rheumatoid arthritis or spondyloarthritis change how the body handles a COVID-19 infection. Researchers compared 150 patients on these drugs with infected family members not on such treatments. The goal was to me…

This early-stage study tested a new radioactive drug called [11C]MC1 to see if it could help PET scans show inflammation in the body. Researchers studied healthy volunteers and people with rheumatoid arthritis or inflammatory muscle disease. The study was stopped early, but the g…