New RA drug trial halted early – what we know

NCT ID NCT06859294

Terminated Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called LY3541860 in 35 adults with moderate-to-severe rheumatoid arthritis who had not improved enough on other treatments. The goal was to see if the drug could reduce joint swelling and pain. However, the trial was terminated early, so the full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LY3541860 (given intravenously)
What this could lead to: If successful, this could point toward a new treatment option for people with rheumatoid arthritis who haven't responded well to other therapies.
What could go wrong: The trial was terminated early and only enrolled 35 people, so results are limited. It is still early-stage research, and the drug may not prove effective or safe in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RHEUMATOID ARTHRITIS

Contacts and locations

Show contact details

Locations

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Avondale

Avondale, Arizona, 85392, United States
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Flagstaff

Flagstaff, Arizona, 86001, United States
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Mesa

Mesa, Arizona, 85210, United States
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Phoenix PV

Phoenix, Arizona, 85032, United States
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Sun City

Sun City, Arizona, 85351, United States
AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Tucson Southeast

Tucson, Arizona, 85748, United States
Accurate Clinical Management, LLC

Baytown, Texas, 77521, United States
Accurate Clinical Research, Inc

Lake Charles, Louisiana, 70605, United States
Accurate Clinical Research, Inc

Houston, Texas, 77089, United States
Altoona Center For Clinical Research

Duncansville, Pennsylvania, 16635, United States
Clinical Research of West Florida

Tampa, Florida, 33606, United States
Clinical Research of West Florida, Inc. (Clearwater)

Clearwater, Florida, 33765, United States
Conquest Research

Winter Park, Florida, 32789, United States
DM Clinical Research - TRA

Tomball, Texas, 77375, United States
Medvin Clinical Research - Covina

Covina, California, 91722, United States
Medvin Clinical Research - Tujunga

Tujunga, California, 91042, United States
Medvin Clinical Research - Whittier

Whittier, California, 90602, United States
Newport Huntington Medical Group

Huntington Beach, California, 92648, United States
Saint Paul Rheumatology

Eagan, Minnesota, 55121, United States
Willow Rheumatology and Wellness PLLC

Willowbrook, Illinois, 60527, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.