Painkiller showdown: which is safer for the heart?

NCT ID NCT03699293

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if one pain reliever interfered more with aspirin's blood-thinning effects. Only 8 people enrolled before the study was stopped early, so results are limited.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sinai Hospital

    Baltimore, Maryland, 21215, United States