RHEUMATOID ARTHRITIS

This study will track 150 people with moderate-to-severe rheumatoid arthritis who have already received an implanted device called the SetPoint System as part of their regular care. The goal is to collect real-world information on how safe the device is, how well it works, and ho…

This study is testing whether a new injectable drug called Natrunix, when added to standard methotrexate treatment, can better control the symptoms of moderate-to-severe rheumatoid arthritis. About 108 adults who still have significant joint pain and swelling despite taking metho…

This study is testing whether a new injectable medication called GenSci120 can help control rheumatoid arthritis in people whose current treatments aren't working well enough. Researchers will compare different doses of GenSci120 against a placebo and an existing arthritis drug (…

This study is testing a new oral medication called ivarmacitinib for people with moderate-to-severe rheumatoid arthritis (RA) who haven't gotten enough relief from common first-line drugs like methotrexate. It aims to see if this pill can better control the disease and reduce sym…

This study aims to see if the rheumatoid arthritis (RA) drug baricitinib changes markers linked to heart disease and blood clot risk. It will compare 100 RA patients taking baricitinib with those on standard treatment over three months. The goal is to better understand the drug's…

This is an early safety study testing a single infusion of stem cells from donated umbilical cords in people with rheumatoid arthritis that current medications don't control well. Sixteen participants will receive either the stem cell treatment or a placebo and be monitored for a…

This early-stage study is testing a new drug called SR-878 in people with rheumatoid arthritis to see if it's safe and to find the right dose for future research. The drug works differently than current treatments by targeting a protein involved in inflammation. Researchers will …

This early-stage study aims to check the safety and measure drug levels of an experimental medication called BMS-986454 in people with rheumatoid arthritis. The trial will enroll 46 participants whose arthritis didn't fully respond to standard methotrexate treatment. Researchers …

This is an early, small study to test the safety and initial effects of a new cell therapy called GC012F for people with difficult-to-treat rheumatoid arthritis (RA). It will enroll 9 adults whose RA has not responded well to multiple standard treatments. Researchers will give pa…

This study is testing whether a combination of resistance exercises and an anti-inflammatory diet can help people with rheumatoid arthritis feel better. It will involve 100 adults who will follow a structured workout and eating plan for 3 months. Researchers will measure changes …

This study aims to understand how two different types of rheumatoid arthritis (RA) treatments affect the body. Researchers will compare patients taking newer JAK inhibitor drugs to those on traditional medications. They will look at blood test results and detailed ultrasound imag…