Poop pills could tame stubborn arthritis

NCT ID NCT07639177

Not yet recruiting Disease control Sponsor: Peking Union Medical College Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether freeze-dried fecal bacteria, given as oral capsules, can improve symptoms in 40 adults with active rheumatoid arthritis that hasn't responded to standard drugs. Participants will receive either the fecal transplant or a placebo for 24 weeks. The main goal is to see if more people in the treatment group achieve at least a 20% or 50% improvement in arthritis symptoms by week 16.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lyophilised oral faecal microbiota (fecal transplant capsules)
What this could lead to: If it works, this could offer a new treatment option for people with rheumatoid arthritis that hasn't responded to standard medications.
What could go wrong: This is a small, early-phase trial with only 40 participants. The treatment may not work better than placebo, and long-term safety is unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RHEUMATOID ARTHRITIS

Contacts and locations

Locations

Peking Union Medical College Hospital

Beijing, Beijing Municipality, 100730, China

More trials for these conditions

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