New pill for rheumatoid arthritis shows promise in early trial
NCT ID NCT07100938
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 study tested an experimental oral drug called BGB-45035 in 49 adults with moderate to severe rheumatoid arthritis who had not responded well to standard treatments. Participants received either the drug or a placebo to see if it could reduce joint pain and swelling. The trial was terminated early, so the full results are not available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BGB-45035 (an oral drug)
What this could lead to
If successful, this could point toward a new oral treatment option for people with rheumatoid arthritis who haven't responded well to standard therapies.
What could go wrong
This trial was terminated early with only 49 participants, so results are limited. The drug may not prove effective or safe in larger studies.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Shenyang, Liaoning, 110000, China
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Affiliated Hospital of Nantong University
Nantong, Jiangsu, 201203, China
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Affiliated Hospital of North Sichuan Medical College
Nanchong, Sichuan, 637000, China
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Anhui Provincial Hospital
Hefei, Anhui, 230000, China
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Beijing Friendship Hospital, Capital Medical University
Beijing, Beijing Municipality, 100050, China
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Chenzhou No1 Peoples Hospital
Chenzhou, Hunan, 423000, China
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Huashan Hospital Fudan University
Shanghai, Shanghai Municipality, 200040, China
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Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, 510515, China
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Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School
Nanjing, Jiangsu, 210008, China
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Nanyang Central Hospital
Nanyang, Henan, 473000, China
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Northern Jiangsu Peoples Hospital
Yangzhou, Jiangsu, 225001, China
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Peking University First Hospital
Beijing, Beijing Municipality, 100034, China
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Pingxiang Peoples Hospital
Pingxiang, Jiangxi, 337055, China
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Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital
Chengdu, Sichuan, 610071, China
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Sun Yat Sen Memorial Hospital, Sun Yat Sen University (North)
Guangzhou, Guangdong, 510000, China
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The Affiliated Hospital of Inner Mongolia Medical University
Hohhot, Inner Mongolia, 010050, China
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The First Affiliated Hospital of Bengbu Medical University
Bengbu, Anhui, 233004, China
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The First Affiliated Hospital of Guangxi Medical University
Nanning, Guangxi, 530021, China
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The First Affiliated Hospital of Henan University of Science and Technology
Luoyang, Henan, 471003, China
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The First Affiliated Hospital of Nanchang University Branch Donghu
Nanchang, Jiangxi, 330006, China
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The First Affiliated Hospital of Xian Jiaotong University
Xi'an, Shaanxi, 710061, China
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The First Affiliated Hospital, Sun Yat Sen University
Guangzhou, Guangdong, 510080, China
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The First Hospital of Jilin University
Changchun, Jilin, 130021, China
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The First Peoples Hospital of Changzhou
Changzhou, Jiangsu, 213000, China
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The Second Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, 400010, China
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The Second Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, 150001, China
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The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310009, China
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The Second Xiangya Hospital of Central South University
Changsha, Hunan, 410011, China
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Zhengzhou Central Hospital
Zhengzhou, Henan, 450007, China