RENAL CELL CARCINOMA

This early-stage study tested a personalized vaccine for people with advanced kidney cancer that had spread. Doctors took cells from a patient's tumor and fused them with special immune-stimulating cells from a donor to create a vaccine. The main goals were to see if the vaccine …

This study tested a combination of two drugs, pembrolizumab and lenvatinib, for people with an advanced form of kidney cancer that had spread and had not been treated before. The goal was to see how well the drugs worked together to shrink tumors and control the cancer. Researche…

This large, completed study tested whether a drug called pembrolizumab could help prevent kidney cancer from returning in patients who had their tumor surgically removed. Nearly 1,000 adults at high risk of the cancer coming back received either the drug or a placebo for about a …

This study tested a new drug called gevokizumab when added to standard cancer treatments. It involved 167 adults with advanced colorectal, gastroesophageal, or kidney cancer that had spread. The main goals were to find a safe and effective dose and to see if the combination could…

This early-stage study tested the safety of combining two experimental drugs, vobramitamab duocarmazine and lorigerlimab, in people with advanced solid tumors that had stopped responding to standard treatments. The main goal was to find a safe dose and see how the body processes …

This study tested whether a 'gut bacteria transplant' could help patients with advanced kidney cancer respond better to immunotherapy drugs. Fifty patients received either a real transplant of healthy gut bacteria from donors or a placebo, alongside their standard cancer treatmen…

This early-stage study tested a new two-step stem cell transplant method for children and young adults whose cancers had returned or didn't respond to standard treatments. The goal was to see if this approach, which uses specially processed cells from a partially matched family d…

This study tested if taking the kidney cancer drug cabozantinib with a light breakfast, instead of on an empty stomach, could make treatment easier and more effective. Researchers enrolled 12 patients to compare how the drug was absorbed by the body under both conditions. The goa…

This study tested whether a new two-drug combination works better than the standard single-drug treatment for advanced kidney cancer that has spread. It involved 861 people who had not yet received treatment for their advanced cancer. Researchers compared the combination of pembr…

This study tested a special recovery program designed to help patients go home faster after minimally invasive kidney cancer surgery. The program included detailed patient education, reduced pain medication use, and encouraged eating, drinking, and moving soon after the operation…

This study looked for early signs in blood and urine that could predict whether advanced kidney cancer treatments are working. Researchers followed 91 patients receiving immunotherapy or targeted drugs, collecting samples during the first 16 weeks of treatment. They compared tiny…

This study tested whether doctors could quickly analyze the genetic makeup of a child's tumor and use that information to choose a personalized treatment plan. It involved 186 children and young adults (up to age 21) whose cancers had returned or did not respond to standard treat…