Zapping kidney cancer: new radiation study aims to avoid surgery

NCT ID NCT02811250

Completed Disease control Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This early-phase study tested stereotactic radiotherapy, a precise type of radiation, on 13 people with small kidney cancers (≤4 cm). The goal was to find the highest safe dose by gradually increasing the radiation in four steps. Participants were followed for up to 5 years to monitor side effects. If proven safe and effective, this approach could offer a quick, non-surgical treatment option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Stereotactic radiotherapy (high-precision radiation)
What this could lead to: If successful, this could point toward a non-invasive, painless alternative to surgery for small kidney cancers.
What could go wrong: This is a very early, small phase I trial with only 13 participants, so results may not apply to all patients. The main goal is safety, not yet effectiveness.

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Conditions

The condition(s) this trial relates to.

kidney cancer renal carcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RENAL CANCER

Contacts and locations

Locations

Service d'Oncologie-Radiothérapie - Centre Hospitalier Lyon Sud - HCL

Pierre-Bénite, 69495, France
Service de Radiothérapie - Centre Georges François Leclerc

Dijon, 21079, France

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